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18 results

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Page 1
The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia.
Nichols E, Merrick R, Hay SI, Himali D, Himali JJ, Hunter S, Keage HAD, Latimer CS, Scott MR, Steinmetz JD, Walker JM, Wharton SB, Wiedner CD, Crane PK, Keene CD, Launer LJ, Matthews FE, Schneider J, Seshadri S, White L, Brayne C, Vos T. Nichols E, et al. Lancet Healthy Longev. 2023 Mar;4(3):e115-e125. doi: 10.1016/S2666-7568(23)00019-3. Lancet Healthy Longev. 2023. PMID: 36870337 Free PMC article.
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts.
Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J, Dickson DW, Dugger BN, Ervin JF, Fleming J, Graff-Radford J, Grinberg LT, Hokkanen SRK, Hunter S, Kapasi A, Kawas CH, Keage HAD, Keene CD, Kero M, Knopman DS, Kouri N, Kovacs GG, Labuzan SA, Larson EB, Latimer CS, Leite REP, Matchett BJ, Matthews FE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Nelson RS, Neltner JH, Nguyen AT, Petersen RC, Polvikoski T, Reichard RR, Rodriguez RD, Suemoto CK, Wang SJ, Wharton SB, White L, Schneider JA. Nelson PT, et al. Acta Neuropathol. 2022 Jul;144(1):27-44. doi: 10.1007/s00401-022-02444-1. Epub 2022 Jun 13. Acta Neuropathol. 2022. PMID: 35697880 Free PMC article.
Heterogeneity of cellular inflammatory responses in ageing white matter and relationship to Alzheimer's and small vessel disease pathologies.
Waller R, Narramore R, Simpson JE, Heath PR, Verma N, Tinsley M, Barnes JR, Haris HT, Henderson FE, Matthews FE, Richardson CD, Brayne C, Ince PG, Kalaria RN, Wharton SB; CFAS. Waller R, et al. Brain Pathol. 2021 May;31(3):e12928. doi: 10.1111/bpa.12928. Epub 2021 Feb 15. Brain Pathol. 2021. PMID: 33336479 Free PMC article.
Epidemiological pathology of Tau in the ageing brain: application of staging for neuropil threads (BrainNet Europe protocol) to the MRC cognitive function and ageing brain study.
Wharton SB, Minett T, Drew D, Forster G, Matthews F, Brayne C, Ince PG; MRC Cognitive Function and Ageing Neuropathology Study Group. Wharton SB, et al. Acta Neuropathol Commun. 2016 Feb 8;4:11. doi: 10.1186/s40478-016-0275-x. Acta Neuropathol Commun. 2016. PMID: 26857919 Free PMC article.
The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain.
Fluteau A, Ince PG, Minett T, Matthews FE, Brayne C, Garwood CJ, Ratcliffe LE, Morgan S, Heath PR, Shaw PJ, Wharton SB, Simpson JE; MRC Cognitive Function Ageing Neuropathology Study Group. Fluteau A, et al. Neurosci Lett. 2015 Nov 16;609:11-7. doi: 10.1016/j.neulet.2015.10.001. Epub 2015 Oct 8. Neurosci Lett. 2015. PMID: 26455863 Free PMC article.
18 results