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Development of a novel apigenin prodrug programmed for alkaline-phosphatase instructed self-inhibition to combat cancer.
Diamantis D, Tsiailanis AD, Papaemmanouil C, Nika MC, Kanaki Z, Golic Grdadolnik S, Babic A, Tzakos EP, Fournier I, Salzet M, Kushwaha PP, Thomaidis NS, Rampias T, Shankar E, Karakurt S, Gupta S, Tzakos AG. Diamantis D, et al. Among authors: tzakos ag. J Biomol Struct Dyn. 2023 Aug 28:1-22. doi: 10.1080/07391102.2023.2247083. Online ahead of print. J Biomol Struct Dyn. 2023. PMID: 37639498
Revisiting bleomycin from pathophysiology to safe clinical use.
Froudarakis M, Hatzimichael E, Kyriazopoulou L, Lagos K, Pappas P, Tzakos AG, Karavasilis V, Daliani D, Papandreou C, Briasoulis E. Froudarakis M, et al. Among authors: tzakos ag. Crit Rev Oncol Hematol. 2013 Jul;87(1):90-100. doi: 10.1016/j.critrevonc.2012.12.003. Epub 2013 Jan 9. Crit Rev Oncol Hematol. 2013. PMID: 23312772 Review.
Novel oncology therapeutics: targeted drug delivery for cancer.
Tzakos AG, Briasoulis E, Thalhammer T, Jäger W, Apostolopoulos V. Tzakos AG, et al. J Drug Deliv. 2013;2013:918304. doi: 10.1155/2013/918304. Epub 2013 Oct 22. J Drug Deliv. 2013. PMID: 24251041 Free PMC article. No abstract available.
GnRH-Gemcitabine conjugates for the treatment of androgen-independent prostate cancer: pharmacokinetic enhancements combined with targeted drug delivery.
Karampelas T, Argyros O, Sayyad N, Spyridaki K, Pappas C, Morgan K, Kolios G, Millar RP, Liapakis G, Tzakos AG, Fokas D, Tamvakopoulos C. Karampelas T, et al. Among authors: tzakos ag. Bioconjug Chem. 2014 Apr 16;25(4):813-23. doi: 10.1021/bc500081g. Epub 2014 Apr 3. Bioconjug Chem. 2014. PMID: 24661240
Direct binding of Bcl-2 family proteins by quercetin triggers its pro-apoptotic activity.
Primikyri A, Chatziathanasiadou MV, Karali E, Kostaras E, Mantzaris MD, Hatzimichael E, Shin JS, Chi SW, Briasoulis E, Kolettas E, Gerothanassis IP, Tzakos AG. Primikyri A, et al. Among authors: tzakos ag. ACS Chem Biol. 2014 Dec 19;9(12):2737-41. doi: 10.1021/cb500259e. Epub 2014 Oct 9. ACS Chem Biol. 2014. PMID: 25211642
148 results