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The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers.
Zanetti-Domingues LC, Korovesis D, Needham SR, Tynan CJ, Sagawa S, Roberts SK, Kuzmanic A, Ortiz-Zapater E, Jain P, Roovers RC, Lajevardipour A, van Bergen En Henegouwen PMP, Santis G, Clayton AHA, Clarke DT, Gervasio FL, Shan Y, Shaw DE, Rolfe DJ, Parker PJ, Martin-Fernandez ML. Zanetti-Domingues LC, et al. Among authors: tynan cj. Nat Commun. 2018 Oct 18;9(1):4325. doi: 10.1038/s41467-018-06632-0. Nat Commun. 2018. PMID: 30337523 Free PMC article.
Single-molecule imaging and fluorescence lifetime imaging microscopy show different structures for high- and low-affinity epidermal growth factor receptors in A431 cells.
Webb SE, Roberts SK, Needham SR, Tynan CJ, Rolfe DJ, Winn MD, Clarke DT, Barraclough R, Martin-Fernandez ML. Webb SE, et al. Among authors: tynan cj. Biophys J. 2008 Feb 1;94(3):803-19. doi: 10.1529/biophysj.107.112623. Epub 2007 Sep 21. Biophys J. 2008. PMID: 17890389 Free PMC article.
Focal adhesions are sites of integrin extension.
Askari JA, Tynan CJ, Webb SE, Martin-Fernandez ML, Ballestrem C, Humphries MJ. Askari JA, et al. Among authors: tynan cj. J Cell Biol. 2010 Mar 22;188(6):891-903. doi: 10.1083/jcb.200907174. Epub 2010 Mar 15. J Cell Biol. 2010. PMID: 20231384 Free PMC article.
A 'pocket guide' to total internal reflection fluorescence.
Martin-Fernandez ML, Tynan CJ, Webb SE. Martin-Fernandez ML, et al. Among authors: tynan cj. J Microsc. 2013 Oct;252(1):16-22. doi: 10.1111/jmi.12070. Epub 2013 Jul 24. J Microsc. 2013. PMID: 23889125 Free PMC article. Review.
24 results