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Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion.
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall JJT, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler EJ, Singh N, Reader CS, Carter EP, Hodivala-Dilke K, Grose RP, Kocher HM, Gavara N, Pearce O, Cutillas P, Marshall JF, Cameron AJM. Murray ER, et al. Among authors: tyler ej. Cell Rep. 2022 Jan 25;38(4):110227. doi: 10.1016/j.celrep.2021.110227. Cell Rep. 2022. PMID: 35081338 Free PMC article.
A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion.
Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M, Boot G, Mackerodt J, Lockley M, Knight MM, Balkwill FR, Pearce OMT. Malacrida B, et al. Among authors: tyler ej. iScience. 2021 May 29;24(6):102676. doi: 10.1016/j.isci.2021.102676. eCollection 2021 Jun 25. iScience. 2021. PMID: 34189439 Free PMC article.
Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis.
Puttock EH, Tyler EJ, Manni M, Maniati E, Butterworth C, Burger Ramos M, Peerani E, Hirani P, Gauthier V, Liu Y, Maniscalco G, Rajeeve V, Cutillas P, Trevisan C, Pozzobon M, Lockley M, Rastrick J, Läubli H, White A, Pearce OMT. Puttock EH, et al. Among authors: tyler ej. Nat Commun. 2023 May 15;14(1):2514. doi: 10.1038/s41467-023-38093-5. Nat Commun. 2023. PMID: 37188691 Free PMC article.
Low Stress Ion Conductance Microscopy of Sub-Cellular Stiffness.
Clarke RW, Novak P, Zhukov A, Tyler EJ, Cano-Jaimez M, Drews A, Richards O, Volynski K, Bishop C, Klenerman D. Clarke RW, et al. Among authors: tyler ej. Soft Matter. 2016 Oct 14;12(38):7953-8. doi: 10.1039/c6sm01106c. Epub 2016 Sep 5. Soft Matter. 2016. PMID: 27604678 Free PMC article.
A multidimensional systems biology analysis of cellular senescence in aging and disease.
Avelar RA, Ortega JG, Tacutu R, Tyler EJ, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K, Johnson E, Murray A, Shields S, Tejada-Martinez D, Thornton D, Fraifeld VE, Bishop CL, de Magalhães JP. Avelar RA, et al. Among authors: tyler ej. Genome Biol. 2020 Apr 7;21(1):91. doi: 10.1186/s13059-020-01990-9. Genome Biol. 2020. PMID: 32264951 Free PMC article.
17 results