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Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study.
Atherton HJ, Dodd MS, Heather LC, Schroeder MA, Griffin JL, Radda GK, Clarke K, Tyler DJ. Atherton HJ, et al. Among authors: tyler dj. Circulation. 2011 Jun 7;123(22):2552-61. doi: 10.1161/CIRCULATIONAHA.110.011387. Epub 2011 May 23. Circulation. 2011. PMID: 21606392 Free PMC article.
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Ashrafian H, Czibik G, Bellahcene M, Aksentijević D, Smith AC, Mitchell SJ, Dodd MS, Kirwan J, Byrne JJ, Ludwig C, Isackson H, Yavari A, Støttrup NB, Contractor H, Cahill TJ, Sahgal N, Ball DR, Birkler RI, Hargreaves I, Tennant DA, Land J, Lygate CA, Johannsen M, Kharbanda RK, Neubauer S, Redwood C, de Cabo R, Ahmet I, Talan M, Günther UL, Robinson AJ, Viant MR, Pollard PJ, Tyler DJ, Watkins H. Ashrafian H, et al. Among authors: tyler dj. Cell Metab. 2012 Mar 7;15(3):361-71. doi: 10.1016/j.cmet.2012.01.017. Cell Metab. 2012. PMID: 22405071 Free PMC article.
219 results