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Non-cytotoxic 1,2,3-triazole tethered fused heterocyclic ring derivatives display Tax protein inhibition and impair HTLV-1 infected cells.
Dos Santos DF, de Pilger DRB, Vandermeulen C, Khouri R, Mantoani SP, Nunes PSG, de Andrade P, Carvalho I, Casseb J, Twizere JC, Willems L, Freitas-Junior L, Kashima S. Dos Santos DF, et al. Among authors: twizere jc. Bioorg Med Chem. 2020 Nov 15;28(22):115746. doi: 10.1016/j.bmc.2020.115746. Epub 2020 Sep 8. Bioorg Med Chem. 2020. PMID: 33007558
Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling.
Twizere JC, Springael JY, Boxus M, Burny A, Dequiedt F, Dewulf JF, Duchateau J, Portetelle D, Urbain P, Van Lint C, Green PL, Mahieux R, Parmentier M, Willems L, Kettmann R. Twizere JC, et al. Blood. 2007 Feb 1;109(3):1051-60. doi: 10.1182/blood-2006-06-026781. Epub 2006 Sep 21. Blood. 2007. PMID: 16990599 Free PMC article.
The HTLV-1 Tax interactome.
Boxus M, Twizere JC, Legros S, Dewulf JF, Kettmann R, Willems L. Boxus M, et al. Among authors: twizere jc. Retrovirology. 2008 Aug 14;5:76. doi: 10.1186/1742-4690-5-76. Retrovirology. 2008. PMID: 18702816 Free PMC article. Review.
The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.
Vandermeulen C, O'Grady T, Wayet J, Galvan B, Maseko S, Cherkaoui M, Desbuleux A, Coppin G, Olivet J, Ben Ameur L, Kataoka K, Ogawa S, Hermine O, Marcais A, Thiry M, Mortreux F, Calderwood MA, Van Weyenbergh J, Peloponese JM, Charloteaux B, Van den Broeke A, Hill DE, Vidal M, Dequiedt F, Twizere JC. Vandermeulen C, et al. Among authors: twizere jc. PLoS Pathog. 2021 Sep 20;17(9):e1009919. doi: 10.1371/journal.ppat.1009919. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34543356 Free PMC article.
The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection.
Beauvois A, Gazon H, Chauhan PS, Jamakhani M, Jacques JR, Thiry M, Dejardin E, Valentin ED, Twizere JC, Péloponèse JM, Njock MS, Yasunaga JI, Matsuoka M, Hamaïdia M, Willems L. Beauvois A, et al. Among authors: twizere jc. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2216127120. doi: 10.1073/pnas.2216127120. Epub 2023 Jul 24. Proc Natl Acad Sci U S A. 2023. PMID: 37487091 Free PMC article.
66 results