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Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.
DeNicola GM, Karreth FA, Humpton TJ, Gopinathan A, Wei C, Frese K, Mangal D, Yu KH, Yeo CJ, Calhoun ES, Scrimieri F, Winter JM, Hruban RH, Iacobuzio-Donahue C, Kern SE, Blair IA, Tuveson DA. DeNicola GM, et al. Among authors: tuveson da. Nature. 2011 Jul 6;475(7354):106-9. doi: 10.1038/nature10189. Nature. 2011. PMID: 21734707 Free PMC article.
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse.
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, Ross S, Conrads TP, Veenstra TD, Hitt BA, Kawaguchi Y, Johann D, Liotta LA, Crawford HC, Putt ME, Jacks T, Wright CV, Hruban RH, Lowy AM, Tuveson DA. Hingorani SR, et al. Among authors: tuveson da. Cancer Cell. 2003 Dec;4(6):437-50. doi: 10.1016/s1535-6108(03)00309-x. Cancer Cell. 2003. PMID: 14706336 Free article.
VAV1: a new target in pancreatic cancer?
Denicola G, Tuveson DA. Denicola G, et al. Among authors: tuveson da. Cancer Biol Ther. 2005 May;4(5):509-11. doi: 10.4161/cbt.4.5.1781. Epub 2005 May 2. Cancer Biol Ther. 2005. PMID: 15970675 Review.
Pancreatic cancer in mice and man: the Penn Workshop 2004.
Hruban RH, Rustgi AK, Brentnall TA, Tempero MA, Wright CV, Tuveson DA. Hruban RH, et al. Among authors: tuveson da. Cancer Res. 2006 Jan 1;66(1):14-7. doi: 10.1158/0008-5472.CAN-05-3914. Cancer Res. 2006. PMID: 16397208
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
King AJ, Patrick DR, Batorsky RS, Ho ML, Do HT, Zhang SY, Kumar R, Rusnak DW, Takle AK, Wilson DM, Hugger E, Wang L, Karreth F, Lougheed JC, Lee J, Chau D, Stout TJ, May EW, Rominger CM, Schaber MD, Luo L, Lakdawala AS, Adams JL, Contractor RG, Smalley KS, Herlyn M, Morrissey MM, Tuveson DA, Huang PS. King AJ, et al. Among authors: tuveson da. Cancer Res. 2006 Dec 1;66(23):11100-5. doi: 10.1158/0008-5472.CAN-06-2554. Cancer Res. 2006. PMID: 17145850
Restoration of p53 function leads to tumour regression in vivo.
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T. Ventura A, et al. Among authors: tuveson da. Nature. 2007 Feb 8;445(7128):661-5. doi: 10.1038/nature05541. Epub 2007 Jan 24. Nature. 2007. PMID: 17251932
241 results