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Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation.
Bárcena C, Stefanovic M, Tutusaus A, Joannas L, Menéndez A, García-Ruiz C, Sancho-Bru P, Marí M, Caballeria J, Rothlin CV, Fernández-Checa JC, de Frutos PG, Morales A. Bárcena C, et al. Among authors: tutusaus a. J Hepatol. 2015 Sep;63(3):670-8. doi: 10.1016/j.jhep.2015.04.013. Epub 2015 Apr 20. J Hepatol. 2015. PMID: 25908269 Free PMC article.
Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma.
Stefanovic M, Tutusaus A, Martinez-Nieto GA, Bárcena C, de Gregorio E, Moutinho C, Barbero-Camps E, Villanueva A, Colell A, Marí M, García-Ruiz C, Fernandez-Checa JC, Morales A. Stefanovic M, et al. Among authors: tutusaus a. Oncotarget. 2016 Feb 16;7(7):8253-67. doi: 10.18632/oncotarget.6982. Oncotarget. 2016. PMID: 26811497 Free PMC article.
A Functional Role of GAS6/TAM in Nonalcoholic Steatohepatitis Progression Implicates AXL as Therapeutic Target.
Tutusaus A, de Gregorio E, Cucarull B, Cristóbal H, Aresté C, Graupera I, Coll M, Colell A, Gausdal G, Lorens JB, García de Frutos P, Morales A, Marí M. Tutusaus A, et al. Cell Mol Gastroenterol Hepatol. 2020;9(3):349-368. doi: 10.1016/j.jcmgh.2019.10.010. Epub 2019 Nov 2. Cell Mol Gastroenterol Hepatol. 2020. PMID: 31689560 Free PMC article.
Mitochondrial Glutathione: Recent Insights and Role in Disease.
Marí M, de Gregorio E, de Dios C, Roca-Agujetas V, Cucarull B, Tutusaus A, Morales A, Colell A. Marí M, et al. Among authors: tutusaus a. Antioxidants (Basel). 2020 Sep 24;9(10):909. doi: 10.3390/antiox9100909. Antioxidants (Basel). 2020. PMID: 32987701 Free PMC article. Review.
18 results