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The oncomodulin receptor ArmC10 enables axon regeneration in mice after nerve injury and neurite outgrowth in human iPSC-derived sensory neurons.
Xie L, Yin Y, Jayakar S, Kawaguchi R, Wang Q, Peterson S, Shi C, Turnes BL, Zhang Z, Oses-Prieto J, Li J, Burlingame A, Woolf CJ, Geschwind D, Rasband M, Benowitz LI. Xie L, et al. Among authors: turnes bl. Sci Transl Med. 2023 Aug 9;15(708):eadg6241. doi: 10.1126/scitranslmed.adg6241. Epub 2023 Aug 9. Sci Transl Med. 2023. PMID: 37556559
Mast cell-derived BH4 is a critical mediator of postoperative pain.
Starkl P, Jonsson G, Artner T, Turnes BL, Serhan N, Oliveira T, Gail LM, Stejskal K, Channon KM, Köcher T, Stary G, Klang V, Gaudenzio N, Knapp S, Woolf CJ, Penninger JM, Cronin SJF. Starkl P, et al. Among authors: turnes bl. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525378. doi: 10.1101/2023.01.24.525378. bioRxiv. 2023. PMID: 37293068 Free PMC article. Preprint.
Crucial neuroprotective roles of the metabolite BH4 in dopaminergic neurons.
Cronin SJF, Yu W, Hale A, Licht-Mayer S, Crabtree MJ, Korecka JA, Tretiakov EO, Sealey-Cardona M, Somlyay M, Onji M, An M, Fox JD, Turnes BL, Gomez-Diaz C, da Luz Scheffer D, Cikes D, Nagy V, Weidinger A, Wolf A, Reither H, Chabloz A, Kavirayani A, Rao S, Andrews N, Latremoliere A, Costigan M, Douglas G, Freitas FC, Pifl C, Walz R, Konrat R, Mahad DJ, Koslov AV, Latini A, Isacson O, Harkany T, Hallett PJ, Bagby S, Woolf CJ, Channon KM, Je HS, Penninger JM. Cronin SJF, et al. Among authors: turnes bl. bioRxiv [Preprint]. 2023 May 8:2023.05.08.539795. doi: 10.1101/2023.05.08.539795. bioRxiv. 2023. PMID: 37214873 Free PMC article. Preprint.
Phenotypic drug screen uncovers the metabolic GCH1/BH4 pathway as key regulator of EGFR/KRAS-mediated neuropathic pain and lung cancer.
Cronin SJF, Rao S, Tejada MA, Turnes BL, Licht-Mayer S, Omura T, Brenneis C, Jacobs E, Barrett L, Latremoliere A, Andrews N, Channon KM, Latini A, Arvanites AC, Davidow LS, Costigan M, Rubin LL, Penninger JM, Woolf CJ. Cronin SJF, et al. Among authors: turnes bl. Sci Transl Med. 2022 Aug 31;14(660):eabj1531. doi: 10.1126/scitranslmed.abj1531. Epub 2022 Aug 31. Sci Transl Med. 2022. PMID: 36044597 Free PMC article.
Automated preclinical detection of mechanical pain hypersensitivity and analgesia.
Zhang Z, Roberson DP, Kotoda M, Boivin B, Bohnslav JP, González-Cano R, Yarmolinsky DA, Turnes BL, Wimalasena NK, Neufeld SQ, Barrett LB, Quintão NLM, Fattori V, Taub DG, Wiltschko AB, Andrews NA, Harvey CD, Datta SR, Woolf CJ. Zhang Z, et al. Among authors: turnes bl. Pain. 2022 Dec 1;163(12):2326-2336. doi: 10.1097/j.pain.0000000000002680. Epub 2022 May 11. Pain. 2022. PMID: 35543646 Free PMC article.
Anti-hyperalgesic properties of ethanolic crude extract from the peels of Citrus reticulata (Rutaceae).
Schneider ACA, Batisti AP, Turnes BL, Martins TC, Lisboa MEM, Custódio KM, Zanco J, Wilson KSC, Heymanns AC, Kanis LA, Magnago RF, Martins DF, Piovezan AP. Schneider ACA, et al. Among authors: turnes bl. An Acad Bras Cienc. 2020;92(1):e20180793. doi: 10.1590/0001-3765202020180793. Epub 2020 May 11. An Acad Bras Cienc. 2020. PMID: 32401835 Free article.
Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM. Cronin SJF, et al. Among authors: turnes bl. Nature. 2019 Aug;572(7769):E18. doi: 10.1038/s41586-019-1459-x. Nature. 2019. PMID: 31363232
Sepiapterin Reductase Inhibition Leading to Selective Reduction of Inflammatory Joint Pain in Mice and Increased Urinary Sepiapterin Levels in Humans and Mice.
Fujita M, Scheffer DDL, Turnes BL, Cronin SJF, Latrémolière A, Costigan M, Woolf CJ, Latini A, Andrews NA. Fujita M, et al. Among authors: turnes bl. Arthritis Rheumatol. 2020 Jan;72(1):57-66. doi: 10.1002/art.41060. Epub 2019 Nov 28. Arthritis Rheumatol. 2020. PMID: 31350812 Free PMC article.
16 results