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247 results

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Page 1
Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Alsamman S, Christenson SA, Yu A, Ayad NME, Mooring MS, Segal JM, Hu JK, Schaub JR, Ho SS, Rao V, Marlow MM, Turner SM, Sedki M, Pantano L, Ghoshal S, Ferreira DDS, Ma HY, Duwaerts CC, Espanol-Suner R, Wei L, Newcomb B, Mileva I, Canals D, Hannun YA, Chung RT, Mattis AN, Fuchs BC, Tager AM, Yimlamai D, Weaver VM, Mullen AC, Sheppard D, Chen JY. Alsamman S, et al. Among authors: turner sm. Sci Transl Med. 2020 Aug 19;12(557):eaay8798. doi: 10.1126/scitranslmed.aay8798. Sci Transl Med. 2020. PMID: 32817366 Free PMC article.
Dual inhibition of αvβ6 and αvβ1 reduces fibrogenesis in lung tissue explants from patients with IPF.
Decaris ML, Schaub JR, Chen C, Cha J, Lee GG, Rexhepaj M, Ho SS, Rao V, Marlow MM, Kotak P, Budi EH, Hooi L, Wu J, Fridlib M, Martin SP, Huang S, Chen M, Muñoz M, Hom TF, Wolters PJ, Desai TJ, Rock F, Leftheris K, Morgans DJ, Lepist EI, Andre P, Lefebvre EA, Turner SM. Decaris ML, et al. Among authors: turner sm. Respir Res. 2021 Oct 19;22(1):265. doi: 10.1186/s12931-021-01863-0. Respir Res. 2021. PMID: 34666752 Free PMC article.
Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice.
Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. Duwaerts CC, et al. Among authors: turner sm. Cell Mol Gastroenterol Hepatol. 2017 Apr 22;4(2):223-236. doi: 10.1016/j.jcmgh.2017.04.004. eCollection 2017 Sep. Cell Mol Gastroenterol Hepatol. 2017. PMID: 28649594 Free PMC article.
Isocaloric manipulation of macronutrients within a high-carbohydrate/moderate-fat diet induces unique effects on hepatic lipogenesis, steatosis and liver injury.
Pierce AA, Duwaerts CC, Soon RK, Siao K, Grenert JP, Fitch M, Hellerstein MK, Beysen C, Turner SM, Maher JJ. Pierce AA, et al. Among authors: turner sm. J Nutr Biochem. 2016 Mar;29:12-20. doi: 10.1016/j.jnutbio.2015.10.020. Epub 2015 Nov 17. J Nutr Biochem. 2016. PMID: 26895660 Free PMC article.
Human sebum requires de novo lipogenesis, which is increased in acne vulgaris and suppressed by acetyl-CoA carboxylase inhibition.
Esler WP, Tesz GJ, Hellerstein MK, Beysen C, Sivamani R, Turner SM, Watkins SM, Amor PA, Carvajal-Gonzalez S, Geoly FJ, Biddle KE, Purkal JJ, Fitch M, Buckeridge C, Silvia AM, Griffith DA, Gorgoglione M, Hassoun L, Bosanac SS, Vera NB, Rolph TP, Pfefferkorn JA, Sonnenberg GE. Esler WP, et al. Among authors: turner sm. Sci Transl Med. 2019 May 15;11(492):eaau8465. doi: 10.1126/scitranslmed.aau8465. Sci Transl Med. 2019. PMID: 31092695 Clinical Trial.
Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib.
Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, Milad M, Hellerstein MK, Luo Z, Kaplan IV, Riese R, Zuckerman A, McInnes IB. Charles-Schoeman C, et al. Among authors: turner sm. Arthritis Rheumatol. 2015 Mar;67(3):616-25. doi: 10.1002/art.38974. Arthritis Rheumatol. 2015. PMID: 25470338 Free PMC article. Clinical Trial.
247 results