Turgeon J - Search Results

1

Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice.

Deodhar M, Al Rihani SB, Arwood MJ, Darakjian L, Dow P, Turgeon J, Michaud V. Deodhar M, et al. Among authors: turgeon j. Pharmaceutics. 2020 Sep 4;12(9):846. doi: 10.3390/pharmaceutics12090846. Pharmaceutics. 2020. PMID: 32899642 Free PMC article. Review.

2

Understanding clopidogrel efficacy in the presence of cytochrome P450 polymorphism.

Turgeon J, Pharand C, Michaud V. Turgeon J, et al. CMAJ. 2006 Jun 6;174(12):1729. doi: 10.1503/cmaj.060502. CMAJ. 2006. PMID: 16754901 Free PMC article. No abstract available.

3

Inhibitory effects of propafenone on the pharmacokinetics of caffeine in humans.

Michaud V, Mouksassi MS, Labbé L, Bélanger PM, Ferron LA, Gilbert M, Grech-Bélanger O, Turgeon J. Michaud V, et al. Among authors: turgeon j. Ther Drug Monit. 2006 Dec;28(6):779-83. doi: 10.1097/01.ftd.0000249945.64978.33. Ther Drug Monit. 2006. PMID: 17164694

4

An improved HPLC assay with fluorescence detection for the determination of domperidone and three major metabolites for application to in vitro drug metabolism studies.

Michaud V, Simard C, Turgeon J. Michaud V, et al. Among authors: turgeon j. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jun 1;852(1-2):611-6. doi: 10.1016/j.jchromb.2007.02.044. Epub 2007 Mar 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17379582

5

Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients.

Michaud V, Vanier MC, Brouillette D, Roy D, Verret L, Noel N, Taillon I, O'Hara G, Gossard D, Champagne M, Goodman K, Renaud Y, Brown A, Phillips M, Ajami AM, Turgeon J. Michaud V, et al. Among authors: turgeon j. Clin Pharmacol Ther. 2008 May;83(5):740-8. doi: 10.1038/sj.clpt.6100434. Epub 2007 Nov 14. Clin Pharmacol Ther. 2008. PMID: 18030307

6

Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination.

Fenneteau F, Turgeon J, Couture L, Michaud V, Li J, Nekka F. Fenneteau F, et al. Among authors: turgeon j. Theor Biol Med Model. 2009 Jan 15;6:2. doi: 10.1186/1742-4682-6-2. Theor Biol Med Model. 2009. PMID: 19146691 Free PMC article.

7

Assessment of competitive and mechanism-based inhibition by clarithromycin: use of domperidone as a CYP3A probe-drug substrate and various enzymatic sources including a new cell-based assay with freshly isolated human hepatocytes.

Michaud V, Turgeon J. Michaud V, et al. Among authors: turgeon j. Drug Metab Lett. 2010 Apr;4(2):69-76. doi: 10.2174/187231210791292717. Drug Metab Lett. 2010. PMID: 20446912

8

Metabolic activity and mRNA levels of human cardiac CYP450s involved in drug metabolism.

Michaud V, Frappier M, Dumas MC, Turgeon J. Michaud V, et al. Among authors: turgeon j. PLoS One. 2010 Dec 14;5(12):e15666. doi: 10.1371/journal.pone.0015666. PLoS One. 2010. PMID: 21179487 Free PMC article.

9

Characterization of CYP3A isozymes involved in the metabolism of domperidone: role of cytochrome b5 and inhibition by ketoconazole.

Michaud V, Simard C, Turgeon J. Michaud V, et al. Among authors: turgeon j. Drug Metab Lett. 2010 Apr;4(2):95-103. doi: 10.2174/187231210791292735. Drug Metab Lett. 2010. PMID: 21281268

10

Combined administration of quinidine and propafenone for atrial fibrillation: the CAQ-PAF study.

O'Hara GE, Philippon F, Gilbert M, Champagne J, Michaud V, Charbonneau L, Pruneau G, Hamelin BA, Geelen P, Turgeon J. O'Hara GE, et al. Among authors: turgeon j. J Clin Pharmacol. 2012 Feb;52(2):171-9. doi: 10.1177/0091270011399574. J Clin Pharmacol. 2012. PMID: 21508180 Clinical Trial.

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