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Highly Potent Host-Specific Small-Molecule Inhibitor of Paramyxovirus and Pneumovirus Replication with High Resistance Barrier.
Shrestha N, Gall FM, Mathieu C, Hierweger MM, Brügger M, Alves MP, Vesin J, Banfi D, Kalbermatter D, Horvat B, Chambon M, Turcatti G, Fotiadis D, Riedl R, Plattet P. Shrestha N, et al. Among authors: turcatti g. mBio. 2021 Dec 21;12(6):e0262121. doi: 10.1128/mBio.02621-21. Epub 2021 Nov 2. mBio. 2021. PMID: 34724816 Free PMC article.
Leads for antitubercular compounds from kinase inhibitor library screens.
Magnet S, Hartkoorn RC, Székely R, Pató J, Triccas JA, Schneider P, Szántai-Kis C, Orfi L, Chambon M, Banfi D, Bueno M, Turcatti G, Kéri G, Cole ST. Magnet S, et al. Among authors: turcatti g. Tuberculosis (Edinb). 2010 Nov;90(6):354-60. doi: 10.1016/j.tube.2010.09.001. Epub 2010 Oct 8. Tuberculosis (Edinb). 2010. PMID: 20934382
Thiol-to-amine cyclization reaction enables screening of large libraries of macrocyclic compounds and the generation of sub-kilodalton ligands.
Kale SS, Bergeron-Brlek M, Wu Y, Kumar MG, Pham MV, Bortoli J, Vesin J, Kong XD, Machado JF, Deyle K, Gonschorek P, Turcatti G, Cendron L, Angelini A, Heinis C. Kale SS, et al. Among authors: turcatti g. Sci Adv. 2019 Aug 21;5(8):eaaw2851. doi: 10.1126/sciadv.aaw2851. eCollection 2019 Aug. Sci Adv. 2019. PMID: 31457083 Free PMC article.
67 results