Tuma-Kellner S - Search Results

1

Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH.

Jansakun C, Chunglok W, Altamura S, Muckenthaler M, Staffer S, Tuma-Kellner S, Merle U, Chamulitrat W. Jansakun C, et al. Among authors: tuma kellner s. Biochim Biophys Acta Mol Basis Dis. 2023 Jan 1;1869(1):166590. doi: 10.1016/j.bbadis.2022.166590. Epub 2022 Nov 2. Biochim Biophys Acta Mol Basis Dis. 2023. PMID: 36334837 Free article.

2

Sensitization to autoimmune hepatitis in group VIA calcium-independent phospholipase A2-null mice led to duodenal villous atrophy with apoptosis, goblet cell hyperplasia and leaked bile acids.

Jiao L, Gan-Schreier H, Tuma-Kellner S, Stremmel W, Chamulitrat W. Jiao L, et al. Biochim Biophys Acta. 2015 Aug;1852(8):1646-57. doi: 10.1016/j.bbadis.2015.04.025. Epub 2015 May 7. Biochim Biophys Acta. 2015. PMID: 25957555 Free article.

3

Deficiency of Group VIA Phospholipase A2 (iPLA2β) Renders Susceptibility for Chemical-Induced Colitis.

Jiao L, Inhoffen J, Gan-Schreier H, Tuma-Kellner S, Stremmel W, Sun Z, Chamulitrat W. Jiao L, et al. Dig Dis Sci. 2015 Dec;60(12):3590-602. doi: 10.1007/s10620-015-3807-5. Epub 2015 Jul 17. Dig Dis Sci. 2015. PMID: 26182903

4

Deficiency of iPLA₂β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma.

Inhoffen J, Tuma-Kellner S, Straub B, Stremmel W, Chamulitrat W. Inhoffen J, et al. Cancers (Basel). 2015 Dec 9;7(4):2427-42. doi: 10.3390/cancers7040901. Cancers (Basel). 2015. PMID: 26690222 Free PMC article.

5

iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.

Deng X, Wang J, Jiao L, Utaipan T, Tuma-Kellner S, Schmitz G, Liebisch G, Stremmel W, Chamulitrat W. Deng X, et al. Biochim Biophys Acta. 2016 May;1861(5):449-61. doi: 10.1016/j.bbalip.2016.02.004. Epub 2016 Feb 9. Biochim Biophys Acta. 2016. PMID: 26873633

6

Ageing sensitized by iPLA₂β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids.

Jiao L, Gan-Schreier H, Zhu X, Wei W, Tuma-Kellner S, Liebisch G, Stremmel W, Chamulitrat W. Jiao L, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Dec;1862(12):1520-1533. doi: 10.1016/j.bbalip.2017.09.001. Epub 2017 Sep 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28888832

7

Elevation of blood lipids in hepatocyte-specific fatty acid transport 4-deficient mice fed with high glucose diets.

Döring S, Seeßle J, Gan-Schreier H, Javaheri B, Jiao L, Cheng Y, Tuma-Kellner S, Liebisch G, Herrmann T, Stremmel W, Chamulitrat W. Döring S, et al. Mol Genet Metab. 2019 Jan;126(1):30-38. doi: 10.1016/j.ymgme.2018.11.010. Epub 2018 Nov 23. Mol Genet Metab. 2019. PMID: 30497809

8

iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes.

Zhu X, Gan-Schreier H, Otto AC, Cheng Y, Staffer S, Tuma-Kellner S, Ganzha A, Liebisch G, Chamulitrat W. Zhu X, et al. Among authors: tuma kellner s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):677-687. doi: 10.1016/j.bbalip.2019.02.003. Epub 2019 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30735854

9

Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.

Otto AC, Gan-Schreier H, Zhu X, Tuma-Kellner S, Staffer S, Ganzha A, Liebisch G, Chamulitrat W. Otto AC, et al. Among authors: tuma kellner s. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 May;1864(5):662-676. doi: 10.1016/j.bbalip.2019.01.012. Epub 2019 Feb 5. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30735855

10

iPla2β Deficiency Suppresses Hepatic ER UPR, Fxr, and Phospholipids in Mice Fed with MCD Diet, Resulting in Exacerbated Hepatic Bile Acids and Biliary Cell Proliferation.

Ming Y, Zhu X, Tuma-Kellner S, Ganzha A, Liebisch G, Gan-Schreier H, Chamulitrat W. Ming Y, et al. Among authors: tuma kellner s. Cells. 2019 Aug 12;8(8):879. doi: 10.3390/cells8080879. Cells. 2019. PMID: 31409057 Free PMC article.

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