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Acid sphingomyelinase promotes SGK1-dependent vascular calcification.
Luong TTD, Tuffaha R, Schuchardt M, Moser B, Schelski N, Boehme B, Gollmann-Tepeköylü C, Schramm C, Holfeld J, Pieske B, Gulbins E, Tölle M, van der Giet M, Lang F, Eckardt KU, Voelkl J, Alesutan I. Luong TTD, et al. Among authors: tuffaha r. Clin Sci (Lond). 2021 Feb 12;135(3):515-534. doi: 10.1042/CS20201122. Clin Sci (Lond). 2021. PMID: 33479769 Free PMC article.
Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB.
Voelkl J, Tuffaha R, Luong TTD, Zickler D, Masyout J, Feger M, Verheyen N, Blaschke F, Kuro-O M, Tomaschitz A, Pilz S, Pasch A, Eckardt KU, Scherberich JE, Lang F, Pieske B, Alesutan I. Voelkl J, et al. Among authors: tuffaha r. J Am Soc Nephrol. 2018 Jun;29(6):1636-1648. doi: 10.1681/ASN.2017050492. Epub 2018 Apr 13. J Am Soc Nephrol. 2018. PMID: 29654213 Free PMC article.
SGK1 induces vascular smooth muscle cell calcification through NF-κB signaling.
Voelkl J, Luong TT, Tuffaha R, Musculus K, Auer T, Lian X, Daniel C, Zickler D, Boehme B, Sacherer M, Metzler B, Kuhl D, Gollasch M, Amann K, Müller DN, Pieske B, Lang F, Alesutan I. Voelkl J, et al. Among authors: tuffaha r. J Clin Invest. 2018 Jul 2;128(7):3024-3040. doi: 10.1172/JCI96477. Epub 2018 Jun 11. J Clin Invest. 2018. PMID: 29889103 Free PMC article.
Protective effects of spironolactone on vascular calcification in chronic kidney disease.
Hammer F, Buehling SS, Masyout J, Malzahn U, Hauser T, Auer T, Grebe S, Feger M, Tuffaha R, Degenhart G, Lang F, Pasch A, Alesutan I, Wanner C, Krane V, Voelkl J. Hammer F, et al. Among authors: tuffaha r. Biochem Biophys Res Commun. 2021 Dec 10;582:28-34. doi: 10.1016/j.bbrc.2021.10.023. Epub 2021 Oct 10. Biochem Biophys Res Commun. 2021. PMID: 34678593 Free article. Clinical Trial.