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Population pharmacokinetic/pharmacodynamic models of JNJ-64794964, a toll-like receptor 7 agonist, in healthy adult participants.
Wu LS, Hu Y, Gane EJ, Slaets L, De Creus A, Ding Y, Niu J, Schwabe C, Goeyvaerts N, Xu Z, Huo D, Tuefferd M, Verbrugge I, Van Remoortere P, Schwertschlag U, Vandenbossche J. Wu LS, et al. Among authors: tuefferd m. Antivir Ther. 2023 Feb;28(1):13596535231151626. doi: 10.1177/13596535231151626. Antivir Ther. 2023. PMID: 36691849 Free article.
A single, oral dose of the TLR7 agonist JNJ-64794964 induces transcriptomic and phenotypic changes in peripheral immune cells in healthy adults.
Pierson W, Tuefferd M, Herschke F, Slaets L, Crabbe M, Verstappen D, De Pelsmaeker S, Strickland I, Gane EJ, Schwabe C, Zhang Y, Meerts P, Vandenbossche J, Van Remoortere P, Verbrugge I, De Creus A. Pierson W, et al. Among authors: tuefferd m. Antivir Ther. 2023 Jun;28(3):13596535231172878. doi: 10.1177/13596535231172878. Antivir Ther. 2023. PMID: 37199270 Free article.
Response of Human Liver Tissue to Innate Immune Stimuli.
Wu X, Roberto JB, Knupp A, Greninger AL, Truong CD, Hollingshead N, Kenerson HL, Tuefferd M, Chen A, Koelle DM, Horton H, Jerome KR, Polyak SJ, Yeung RS, Crispe IN. Wu X, et al. Among authors: tuefferd m. Front Immunol. 2022 Mar 9;13:811551. doi: 10.3389/fimmu.2022.811551. eCollection 2022. Front Immunol. 2022. PMID: 35355993 Free PMC article.
Precision-cut human liver slice cultures as an immunological platform.
Wu X, Roberto JB, Knupp A, Kenerson HL, Truong CD, Yuen SY, Brempelis KJ, Tuefferd M, Chen A, Horton H, Yeung RS, Crispe IN. Wu X, et al. Among authors: tuefferd m. J Immunol Methods. 2018 Apr;455:71-79. doi: 10.1016/j.jim.2018.01.012. Epub 2018 Feb 1. J Immunol Methods. 2018. PMID: 29408707 Free PMC article.
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.
McGowan DC, Herschke F, Pauwels F, Stoops B, Smyej I, Last S, Pieters S, Embrechts W, Khamlichi MD, Thoné T, Van Schoubroeck B, Mostmans W, Wuyts D, Verstappen D, Scholliers A, De Pooter D, Dhuyvetter D, Borghys H, Tuefferd M, Arnoult E, Hong J, Fanning G, Bollekens J, Urmaliya V, Teisman A, Horton H, Jonckers THM, Raboisson P. McGowan DC, et al. Among authors: tuefferd m. J Med Chem. 2017 Jul 27;60(14):6137-6151. doi: 10.1021/acs.jmedchem.7b00365. Epub 2017 Jul 14. J Med Chem. 2017. PMID: 28671847
Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells.
Baud A, Wessely F, Mazzacuva F, McCormick J, Camuzeaux S, Heywood WE, Little D, Vowles J, Tuefferd M, Mosaku O, Lako M, Armstrong L, Webber C, Cader MZ, Peeters P, Gissen P, Cowley SA, Mills K. Baud A, et al. Among authors: tuefferd m. Anal Chem. 2017 Feb 21;89(4):2440-2448. doi: 10.1021/acs.analchem.6b04368. Epub 2017 Feb 6. Anal Chem. 2017. PMID: 28192931
Sustained synchronized neuronal network activity in a human astrocyte co-culture system.
Kuijlaars J, Oyelami T, Diels A, Rohrbacher J, Versweyveld S, Meneghello G, Tuefferd M, Verstraelen P, Detrez JR, Verschuuren M, De Vos WH, Meert T, Peeters PJ, Cik M, Nuydens R, Brône B, Verheyen A. Kuijlaars J, et al. Among authors: tuefferd m. Sci Rep. 2016 Nov 7;6:36529. doi: 10.1038/srep36529. Sci Rep. 2016. PMID: 27819315 Free PMC article.
23 results