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The anti-cancer agent guttiferone-A permeabilizes mitochondrial membrane: ensuing energetic and oxidative stress implications.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: tudella vg. Toxicol Appl Pharmacol. 2011 Jun 15;253(3):282-9. doi: 10.1016/j.taap.2011.04.011. Epub 2011 Apr 27. Toxicol Appl Pharmacol. 2011. PMID: 21549140 Free article.
The anti-cancer agent nemorosone is a new potent protonophoric mitochondrial uncoupler.
Pardo-Andreu GL, Nuñez-Figueredo Y, Tudella VG, Cuesta-Rubio O, Rodrigues FP, Pestana CR, Uyemura SA, Leopoldino AM, Alberici LC, Curti C. Pardo-Andreu GL, et al. Among authors: tudella vg. Mitochondrion. 2011 Mar;11(2):255-63. doi: 10.1016/j.mito.2010.10.008. Epub 2010 Oct 31. Mitochondrion. 2011. PMID: 21044702