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Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice.
Stein M, Barnea-Zohar M, Shalev M, Arman E, Brenner O, Winograd-Katz S, Gerstung J, Thalji F, Kanaan M, Elinav H, Stepensky P, Geiger B, Tuckermann J, Elson A. Stein M, et al. Among authors: tuckermann j. Bone. 2020 Jul;136:115360. doi: 10.1016/j.bone.2020.115360. Epub 2020 Apr 8. Bone. 2020. PMID: 32278070
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts.
Barnea-Zohar M, Winograd-Katz SE, Shalev M, Arman E, Reuven N, Roth L, Golani O, Stein M, Thalji F, Kanaan M, Tuckermann J, Geiger B, Elson A. Barnea-Zohar M, et al. Among authors: tuckermann j. J Cell Sci. 2021 May 1;134(9):jcs254979. doi: 10.1242/jcs.254979. Epub 2021 May 11. J Cell Sci. 2021. PMID: 33975343 Free PMC article.
Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis.
Liu P, Lee S, Knoll J, Rauch A, Ostermay S, Luther J, Malkusch N, Lerner UH, Zaiss MM, Neven M, Wittig R, Rauner M, David JP, Bertolino P, Zhang CX, Tuckermann JP. Liu P, et al. Among authors: tuckermann jp. Cell Death Differ. 2017 Apr;24(4):672-682. doi: 10.1038/cdd.2016.165. Epub 2017 Jan 20. Cell Death Differ. 2017. PMID: 28106886 Free PMC article.
Induced global deletion of glucocorticoid receptor impairs fracture healing.
Rapp AE, Hachemi Y, Kemmler J, Koenen M, Tuckermann J, Ignatius A. Rapp AE, et al. Among authors: tuckermann j. FASEB J. 2018 Apr;32(4):2235-2245. doi: 10.1096/fj.201700459RR. Epub 2018 Jan 5. FASEB J. 2018. PMID: 29217668 Free PMC article.
Collectively, our data show that the absence of the GR significantly impairs fracture healing associated with a defective cartilage-to-bone transition, underscoring an important role of GCs during fracture healing.-Rapp, A. E., Hachemi, Y., Kemmler, J., Koenen, M., Tuck …
Collectively, our data show that the absence of the GR significantly impairs fracture healing associated with a defective cartilage-to-bone …
188 results