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Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways.
Oncotarget. 2017 Feb 28;8(9):14604-14619. doi: 10.18632/oncotarget.14654.
Oncotarget. 2017.
PMID: 28099937
Free PMC article.
Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death.
Piazza F, Manni S, Tubi LQ, Montini B, Pavan L, Colpo A, Gnoato M, Cabrelle A, Adami F, Zambello R, Trentin L, Gurrieri C, Semenzato G.
Piazza F, et al. Among authors: tubi lq.
BMC Cancer. 2010 Oct 4;10:526. doi: 10.1186/1471-2407-10-526.
BMC Cancer. 2010.
PMID: 20920357
Free PMC article.
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Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bortezomib on multiple myeloma and mantle cell lymphoma cells.
Manni S, Brancalion A, Mandato E, Tubi LQ, Colpo A, Pizzi M, Cappellesso R, Zaffino F, Di Maggio SA, Cabrelle A, Marino F, Zambello R, Trentin L, Adami F, Gurrieri C, Semenzato G, Piazza F.
Manni S, et al. Among authors: tubi lq.
PLoS One. 2013 Sep 27;8(9):e75280. doi: 10.1371/journal.pone.0075280. eCollection 2013.
PLoS One. 2013.
PMID: 24086494
Free PMC article.
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Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.
Manni S, Brancalion A, Tubi LQ, Colpo A, Pavan L, Cabrelle A, Ave E, Zaffino F, Di Maira G, Ruzzene M, Adami F, Zambello R, Pitari MR, Tassone P, Pinna LA, Gurrieri C, Semenzato G, Piazza F.
Manni S, et al. Among authors: tubi lq.
Clin Cancer Res. 2012 Apr 1;18(7):1888-900. doi: 10.1158/1078-0432.CCR-11-1789. Epub 2012 Feb 20.
Clin Cancer Res. 2012.
PMID: 22351691
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CX-4945, a Selective Inhibitor of Casein Kinase 2, Synergizes with B Cell Receptor Signaling Inhibitors in Inducing Diffuse Large B Cell Lymphoma Cell Death.
Mandato E, Nunes SC, Zaffino F, Casellato A, Macaccaro P, Tubi LQ, Visentin A, Trentin L, Semenzato G, Piazza F.
Mandato E, et al. Among authors: tubi lq.
Curr Cancer Drug Targets. 2018;18(6):608-616. doi: 10.2174/1568009617666170427110450.
Curr Cancer Drug Targets. 2018.
PMID: 28460620
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Metabolic control of epigenetic rearrangements in B cell pathophysiology.
Calciolari B, Scarpinello G, Tubi LQ, Piazza F, Carrer A.
Calciolari B, et al. Among authors: tubi lq.
Open Biol. 2022 May;12(5):220038. doi: 10.1098/rsob.220038. Epub 2022 May 18.
Open Biol. 2022.
PMID: 35580618
Free PMC article.
Review.
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