Tu C - Search Results

1

A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX.

Pinard MA, Aggarwal M, Mahon BP, Tu C, McKenna R. Pinard MA, et al. Among authors: tu c. Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1352-8. doi: 10.1107/S2053230X1501239X. Epub 2015 Sep 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26457530 Free PMC article.

2

Crystallization and preliminary X-ray analysis of human carbonic anhydrase III.

Duda DM, Yoshioka C, Govindasamy L, An H, Tu C, Silverman DN, McKenna R. Duda DM, et al. Among authors: tu c. Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):849-52. doi: 10.1107/s0907444902003700. Epub 2002 Apr 26. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 11976500

3

The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.

Duda D, Govindasamy L, Agbandje-McKenna M, Tu C, Silverman DN, McKenna R. Duda D, et al. Among authors: tu c. Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):93-104. doi: 10.1107/s0907444902019455. Epub 2002 Dec 19. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12499545

4

Structure of human salivary alpha-amylase crystallized in a C-centered monoclinic space group.

Fisher SZ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rajaniemi HJ, McKenna R. Fisher SZ, et al. Among authors: tu c. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Feb 1;62(Pt 2):88-93. doi: 10.1107/S1744309105042491. Epub 2006 Jan 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 16511271 Free PMC article.

5

Location of binding sites in small molecule rescue of human carbonic anhydrase II.

Bhatt D, Fisher SZ, Tu C, McKenna R, Silverman DN. Bhatt D, et al. Among authors: tu c. Biophys J. 2007 Jan 15;92(2):562-70. doi: 10.1529/biophysj.106.093203. Epub 2006 Oct 27. Biophys J. 2007. PMID: 17071654 Free PMC article.

6

Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties.

Genis C, Sippel KH, Case N, Cao W, Avvaru BS, Tartaglia LJ, Govindasamy L, Tu C, Agbandje-McKenna M, Silverman DN, Rosser CJ, McKenna R. Genis C, et al. Among authors: tu c. Biochemistry. 2009 Feb 17;48(6):1322-31. doi: 10.1021/bi802035f. Biochemistry. 2009. PMID: 19170619 Free PMC article.

7

Role of zinc in catalytic activity of carbonic anhydrase IX.

Tu C, Foster L, Alvarado A, McKenna R, Silverman DN, Frost SC. Tu C, et al. Arch Biochem Biophys. 2012 May;521(1-2):90-4. doi: 10.1016/j.abb.2012.03.017. Epub 2012 Mar 23. Arch Biochem Biophys. 2012. PMID: 22465027 Free PMC article.

8

Water networks in fast proton transfer during catalysis by human carbonic anhydrase II.

Mikulski R, West D, Sippel KH, Avvaru BS, Aggarwal M, Tu C, McKenna R, Silverman DN. Mikulski R, et al. Among authors: tu c. Biochemistry. 2013 Jan 8;52(1):125-31. doi: 10.1021/bi301099k. Epub 2012 Dec 18. Biochemistry. 2013. PMID: 23215152 Free PMC article.

9

Effects of cryoprotectants on the structure and thermostability of the human carbonic anhydrase II-acetazolamide complex.

Aggarwal M, Boone CD, Kondeti B, Tu C, Silverman DN, McKenna R. Aggarwal M, et al. Among authors: tu c. Acta Crystallogr D Biol Crystallogr. 2013 May;69(Pt 5):860-5. doi: 10.1107/S0907444913002771. Epub 2013 Apr 19. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23633596 Free PMC article.

10

Structural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bond.

Boone CD, Habibzadegan A, Tu C, Silverman DN, McKenna R. Boone CD, et al. Among authors: tu c. Acta Crystallogr D Biol Crystallogr. 2013 Aug;69(Pt 8):1414-22. doi: 10.1107/S0907444913008743. Epub 2013 Jul 13. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23897465 Free PMC article.

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