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IL-2-driven CD8+ T cell phenotypes: implications for immunotherapy.
Trends Immunol. 2023 Nov;44(11):890-901. doi: 10.1016/j.it.2023.09.003. Epub 2023 Oct 10.
Trends Immunol. 2023.
PMID: 37827864
Free PMC article.
Review.
Regulatory T cells suppress the formation of potent KLRK1 and IL-7R expressing effector CD8 T cells by limiting IL-2.
Tsyklauri O, Chadimova T, Niederlova V, Kovarova J, Michalik J, Malatova I, Janusova S, Ivashchenko O, Rossez H, Drobek A, Vecerova H, Galati V, Kovar M, Stepanek O.
Tsyklauri O, et al.
Elife. 2023 Jan 27;12:e79342. doi: 10.7554/eLife.79342.
Elife. 2023.
PMID: 36705564
Free PMC article.
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Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells.
Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, Schober K, Busch DH, Weiss A, Huppa JB, Stepanek O.
Horkova V, et al. Among authors: tsyklauri o.
Nat Immunol. 2023 Jan;24(1):174-185. doi: 10.1038/s41590-022-01366-0. Epub 2022 Dec 23.
Nat Immunol. 2023.
PMID: 36564464
Free PMC article.
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CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology.
Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, Ujevic A, Stefanovic J, Drobek A, Huranova M, Niederlova V, Tsyklauri O, Neuwirth A, Tureckova J, Stepanek O, Draber P.
Knizkova D, et al. Among authors: tsyklauri o.
Nat Immunol. 2022 Nov;23(11):1644-1652. doi: 10.1038/s41590-022-01325-9. Epub 2022 Oct 21.
Nat Immunol. 2022.
PMID: 36271145
Free PMC article.
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CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties.
Niederlova V, Tsyklauri O, Chadimova T, Stepanek O.
Niederlova V, et al. Among authors: tsyklauri o.
Eur J Immunol. 2021 Mar;51(3):512-530. doi: 10.1002/eji.202048614. Epub 2021 Feb 19.
Eur J Immunol. 2021.
PMID: 33501647
Free article.
Review.
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Bardet-Biedl Syndrome ciliopathy is linked to altered hematopoiesis and dysregulated self-tolerance.
Tsyklauri O, Niederlova V, Forsythe E, Prasai A, Drobek A, Kasparek P, Sparks K, Trachtulec Z, Prochazka J, Sedlacek R, Beales P, Huranova M, Stepanek O.
Tsyklauri O, et al.
EMBO Rep. 2021 Feb 3;22(2):e50785. doi: 10.15252/embr.202050785. Epub 2021 Jan 11.
EMBO Rep. 2021.
PMID: 33426789
Free PMC article.
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Toll-like receptor signaling in thymic epithelium controls monocyte-derived dendritic cell recruitment and Treg generation.
Vobořil M, Brabec T, Dobeš J, Šplíchalová I, Březina J, Čepková A, Dobešová M, Aidarova A, Kubovčiak J, Tsyklauri O, Štěpánek O, Beneš V, Sedláček R, Klein L, Kolář M, Filipp D.
Vobořil M, et al. Among authors: tsyklauri o.
Nat Commun. 2020 May 12;11(1):2361. doi: 10.1038/s41467-020-16081-3.
Nat Commun. 2020.
PMID: 32398640
Free PMC article.
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Meta-analysis of genotype-phenotype associations in Bardet-Biedl syndrome uncovers differences among causative genes.
Niederlova V, Modrak M, Tsyklauri O, Huranova M, Stepanek O.
Niederlova V, et al. Among authors: tsyklauri o.
Hum Mutat. 2019 Nov;40(11):2068-2087. doi: 10.1002/humu.23862. Epub 2019 Jul 29.
Hum Mutat. 2019.
PMID: 31283077
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