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Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury.
Miljkovic JL, Burger N, Gawel JM, Mulvey JF, Norman AAI, Nishimura T, Tsujihata Y, Logan A, Sauchanka O, Caldwell ST, Morris JL, Prime TA, Warrington S, Prudent J, Bates GR, Aksentijević D, Prag HA, James AM, Krieg T, Hartley RC, Murphy MP. Miljkovic JL, et al. Among authors: tsujihata y. Redox Biol. 2022 Sep;55:102429. doi: 10.1016/j.redox.2022.102429. Epub 2022 Aug 5. Redox Biol. 2022. PMID: 35961099 Free PMC article.
Visualizing and Modulating Mitophagy for Therapeutic Studies of Neurodegeneration.
Katayama H, Hama H, Nagasawa K, Kurokawa H, Sugiyama M, Ando R, Funata M, Yoshida N, Homma M, Nishimura T, Takahashi M, Ishida Y, Hioki H, Tsujihata Y, Miyawaki A. Katayama H, et al. Among authors: tsujihata y. Cell. 2020 May 28;181(5):1176-1187.e16. doi: 10.1016/j.cell.2020.04.025. Epub 2020 May 20. Cell. 2020. PMID: 32437660 Free article.
Discovery of a novel series of GPR119 agonists: Design, synthesis, and biological evaluation of N-(Piperidin-4-yl)-N-(trifluoromethyl)pyrimidin-4-amine derivatives.
Kubo O, Takami K, Kamaura M, Watanabe K, Miyashita H, Abe S, Matsuda K, Tsujihata Y, Odani T, Iwasaki S, Kitazaki T, Murata T, Sato K. Kubo O, et al. Among authors: tsujihata y. Bioorg Med Chem. 2021 Jul 1;41:116208. doi: 10.1016/j.bmc.2021.116208. Epub 2021 May 9. Bioorg Med Chem. 2021. PMID: 34010766 Free article.
Discovery of a novel series of indolinylpyrimidine-based GPR119 agonists: Elimination of ether-a-go-go-related gene liability using a hydrogen bond acceptor-focused approach.
Kamaura M, Kubo O, Sugimoto H, Noguchi N, Miyashita H, Abe S, Matsuda K, Tsujihata Y, Odani T, Iwasaki S, Murata T, Sato K. Kamaura M, et al. Among authors: tsujihata y. Bioorg Med Chem. 2021 Mar 15;34:116034. doi: 10.1016/j.bmc.2021.116034. Epub 2021 Jan 23. Bioorg Med Chem. 2021. PMID: 33548803 Free article.
24 results