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Stress- and ubiquitylation-dependent phase separation of the proteasome.
Yasuda S, Tsuchiya H, Kaiho A, Guo Q, Ikeuchi K, Endo A, Arai N, Ohtake F, Murata S, Inada T, Baumeister W, Fernández-Busnadiego R, Tanaka K, Saeki Y. Yasuda S, et al. Among authors: tsuchiya h. Nature. 2020 Feb;578(7794):296-300. doi: 10.1038/s41586-020-1982-9. Epub 2020 Feb 5. Nature. 2020. PMID: 32025036
Ubiquitin is phosphorylated by PINK1 to activate parkin.
Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N. Koyano F, et al. Among authors: tsuchiya h. Nature. 2014 Jun 5;510(7503):162-6. doi: 10.1038/nature13392. Epub 2014 Jun 4. Nature. 2014. PMID: 24784582
Ubiquitin acetylation inhibits polyubiquitin chain elongation.
Ohtake F, Saeki Y, Sakamoto K, Ohtake K, Nishikawa H, Tsuchiya H, Ohta T, Tanaka K, Kanno J. Ohtake F, et al. Among authors: tsuchiya h. EMBO Rep. 2015 Feb;16(2):192-201. doi: 10.15252/embr.201439152. Epub 2014 Dec 19. EMBO Rep. 2015. PMID: 25527407 Free PMC article.
The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.
Morimoto D, Walinda E, Fukada H, Sou YS, Kageyama S, Hoshino M, Fujii T, Tsuchiya H, Saeki Y, Arita K, Ariyoshi M, Tochio H, Iwai K, Namba K, Komatsu M, Tanaka K, Shirakawa M. Morimoto D, et al. Among authors: tsuchiya h. Nat Commun. 2015 Jan 20;6:6116. doi: 10.1038/ncomms7116. Nat Commun. 2015. PMID: 25600778 Free PMC article.
A comprehensive method for detecting ubiquitinated substrates using TR-TUBE.
Yoshida Y, Saeki Y, Murakami A, Kawawaki J, Tsuchiya H, Yoshihara H, Shindo M, Tanaka K. Yoshida Y, et al. Among authors: tsuchiya h. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4630-5. doi: 10.1073/pnas.1422313112. Epub 2015 Mar 31. Proc Natl Acad Sci U S A. 2015. PMID: 25827227 Free PMC article.
The emerging complexity of ubiquitin architecture.
Ohtake F, Tsuchiya H. Ohtake F, et al. Among authors: tsuchiya h. J Biochem. 2017 Feb 1;161(2):125-133. doi: 10.1093/jb/mvw088. J Biochem. 2017. PMID: 28011818 Review.
1,777 results