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Page 1
Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
van Straalen KR, Ma F, Tsou PS, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. van Straalen KR, et al. Among authors: tsou ps. J Clin Invest. 2024 Feb 1;134(3):e169225. doi: 10.1172/JCI169225. J Clin Invest. 2024. PMID: 38051587 Free PMC article.
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.
Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM. Sarkar MK, et al. Among authors: tsou ps. Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18. Ann Rheum Dis. 2018. PMID: 30021804 Free PMC article.
Inhibition of bromodomain extraterminal histone readers alleviates skin fibrosis in experimental models of scleroderma.
Vichaikul S, Gurrea-Rubio M, Amin MA, Campbell PL, Wu Q, Mattichak MN, Brodie WD, Palisoc PJ, Ali M, Muraoka S, Ruth JH, Model EN, Rohraff DM, Hervoso JL, Mao-Draayer Y, Fox DA, Khanna D, Sawalha AH, Tsou PS. Vichaikul S, et al. Among authors: tsou ps. JCI Insight. 2022 May 9;7(9):e150871. doi: 10.1172/jci.insight.150871. JCI Insight. 2022. PMID: 35349485 Free PMC article.
Soluble CD13 induces inflammatory arthritis by activating the bradykinin receptor B1.
Tsou PS, Lu C, Gurrea-Rubio M, Muraoka S, Campbell PL, Wu Q, Model EN, Lind ME, Vichaikul S, Mattichak MN, Brodie WD, Hervoso JL, Ory S, Amarista CI, Pervez R, Junginger L, Ali M, Hodish G, O'Mara MM, Ruth JH, Robida AM, Alt AJ, Zhang C, Urquhart AG, Lawton JN, Chung KC, Maerz T, Saunders TL, Groppi VE, Fox DA, Amin MA. Tsou PS, et al. J Clin Invest. 2022 Jun 1;132(11):e151827. doi: 10.1172/JCI151827. J Clin Invest. 2022. PMID: 35439173 Free PMC article.
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, Perez White BE, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. Sapao P, et al. Among authors: tsou ps. J Invest Dermatol. 2023 Feb;143(2):284-293. doi: 10.1016/j.jid.2022.08.052. Epub 2022 Sep 15. J Invest Dermatol. 2023. PMID: 36116512 Free PMC article.
Senescent Cells Accumulate in Systemic Sclerosis Skin.
Shi B, Tsou PS, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. Shi B, et al. Among authors: tsou ps. J Invest Dermatol. 2023 Apr;143(4):661-664.e5. doi: 10.1016/j.jid.2022.09.652. Epub 2022 Sep 30. J Invest Dermatol. 2023. PMID: 36191640 Free PMC article. No abstract available.
Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis.
Xing E, Ma F, Wasikowski R, Billi AC, Gharaee-Kermani M, Fox J, Dobry C, Victory A, Sarkar MK, Xing X, Plazyo O, Chen HW, Barber G, Jacobe H, Tsou PS, Modlin RL, Varga J, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Khanna D. Xing E, et al. Among authors: tsou ps. JCI Insight. 2023 Aug 22;8(16):e171307. doi: 10.1172/jci.insight.171307. JCI Insight. 2023. PMID: 37471168 Free PMC article.
Activation of Cytotoxic Lymphocytes Through CD6 Enhances Killing of Cancer Cells.
Gurrea-Rubio M, Wu Q, Amin MA, Tsou PS, Campbell PL, Amarista CE, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Gurrea-Rubio M, et al. Among authors: tsou ps. Res Sq [Preprint]. 2023 Oct 9:rs.3.rs-3405677. doi: 10.21203/rs.3.rs-3405677/v1. Res Sq. 2023. PMID: 37886483 Free PMC article. Updated. Preprint.
65 results