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Rare Antagonistic Leptin Variants and Severe, Early-Onset Obesity.
Funcke JB, Moepps B, Roos J, von Schnurbein J, Verstraete K, Fröhlich-Reiterer E, Kohlsdorf K, Nunziata A, Brandt S, Tsirigotaki A, Dansercoer A, Suppan E, Haris B, Debatin KM, Savvides SN, Farooqi IS, Hussain K, Gierschik P, Fischer-Posovszky P, Wabitsch M. Funcke JB, et al. Among authors: tsirigotaki a. N Engl J Med. 2023 Jun 15;388(24):2253-2261. doi: 10.1056/NEJMoa2204041. N Engl J Med. 2023. PMID: 37314706
Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Tsirigotaki A, Dansercoer A, Verschueren KHG, Marković I, Pollmann C, Hafer M, Felix J, Birck C, Van Putte W, Catteeuw D, Tavernier J, Fernando Bazan J, Piehler J, Savvides SN, Verstraete K. Tsirigotaki A, et al. Nat Struct Mol Biol. 2023 Apr;30(4):551-563. doi: 10.1038/s41594-023-00941-9. Epub 2023 Mar 23. Nat Struct Mol Biol. 2023. PMID: 36959263
Evolutionary adaptation of the protein folding pathway for secretability.
Smets D, Tsirigotaki A, Smit JH, Krishnamurthy S, Portaliou AG, Vorobieva A, Vranken W, Karamanou S, Economou A. Smets D, et al. Among authors: tsirigotaki a. EMBO J. 2022 Dec 1;41(23):e111344. doi: 10.15252/embj.2022111344. Epub 2022 Aug 29. EMBO J. 2022. PMID: 36031863 Free PMC article.
Structural dynamics in the evolution of a bilobed protein scaffold.
Gouridis G, Muthahari YA, de Boer M, Griffith DA, Tsirigotaki A, Tassis K, Zijlstra N, Xu R, Eleftheriadis N, Sugijo Y, Zacharias M, Dömling A, Karamanou S, Pozidis C, Economou A, Cordes T. Gouridis G, et al. Among authors: tsirigotaki a. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2026165118. doi: 10.1073/pnas.2026165118. Proc Natl Acad Sci U S A. 2021. PMID: 34845009 Free PMC article.
Structural Basis of the Subcellular Topology Landscape of Escherichia coli.
Loos MS, Ramakrishnan R, Vranken W, Tsirigotaki A, Tsare EP, Zorzini V, Geyter J, Yuan B, Tsamardinos I, Klappa M, Schymkowitz J, Rousseau F, Karamanou S, Economou A. Loos MS, et al. Among authors: tsirigotaki a. Front Microbiol. 2019 Jul 24;10:1670. doi: 10.3389/fmicb.2019.01670. eCollection 2019. Front Microbiol. 2019. PMID: 31404336 Free PMC article.
Long-Lived Folding Intermediates Predominate the Targeting-Competent Secretome.
Tsirigotaki A, Chatzi KE, Koukaki M, De Geyter J, Portaliou AG, Orfanoudaki G, Sardis MF, Trelle MB, Jørgensen TJD, Karamanou S, Economou A. Tsirigotaki A, et al. Structure. 2018 May 1;26(5):695-707.e5. doi: 10.1016/j.str.2018.03.006. Epub 2018 Apr 5. Structure. 2018. PMID: 29606594 Free article.
Hierarchical protein targeting and secretion is controlled by an affinity switch in the type III secretion system of enteropathogenic Escherichia coli.
Portaliou AG, Tsolis KC, Loos MS, Balabanidou V, Rayo J, Tsirigotaki A, Crepin VF, Frankel G, Kalodimos CG, Karamanou S, Economou A. Portaliou AG, et al. Among authors: tsirigotaki a. EMBO J. 2017 Dec 1;36(23):3517-3531. doi: 10.15252/embj.201797515. Epub 2017 Nov 6. EMBO J. 2017. PMID: 29109154 Free PMC article.
16 results