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Intracellular delivery of full length recombinant human mitochondrial L-Sco2 protein into the mitochondria of permanent cell lines and SCO2 deficient patient's primary cells.
Foltopoulou PF, Tsiftsoglou AS, Bonovolias ID, Ingendoh AT, Papadopoulou LC. Foltopoulou PF, et al. Among authors: tsiftsoglou as. Biochim Biophys Acta. 2010 Jun;1802(6):497-508. doi: 10.1016/j.bbadis.2010.02.009. Epub 2010 Mar 1. Biochim Biophys Acta. 2010. PMID: 20193760 Free article.
Production and Transduction of a Human Recombinant β-Globin Chain into Proerythroid K-562 Cells To Replace Missing Endogenous β-Globin.
Papadopoulou LC, Ingendoh-Tsakmakidis A, Mpoutoureli CN, Tzikalou LD, Spyridou ED, Gavriilidis GI, Kaiafas GC, Ntaska AT, Vlachaki E, Panayotou G, Samiotaki M, Tsiftsoglou AS. Papadopoulou LC, et al. Among authors: tsiftsoglou as. Mol Pharm. 2018 Dec 3;15(12):5665-5677. doi: 10.1021/acs.molpharmaceut.8b00857. Epub 2018 Nov 12. Mol Pharm. 2018. PMID: 30375878
In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations.
Kaiafas GC, Papagiannopoulou D, Miliotou ΑN, Tsingotjidou AS, Chalkidou PC, Tsika AC, Spyroulias GA, Tsiftsoglou AS, Papadopoulou LC. Kaiafas GC, et al. Among authors: tsiftsoglou as. Mol Genet Metab Rep. 2020 Dec 8;25:100683. doi: 10.1016/j.ymgmr.2020.100683. eCollection 2020 Dec. Mol Genet Metab Rep. 2020. PMID: 33318931 Free PMC article.
PTD-mediated delivery of α-globin chain into Κ-562 erythroleukemia cells and α-thalassemic (HBH) patients' RBCs ex vivo in the frame of Protein Replacement Therapy.
Miliotou AN, Papagiannopoulou D, Vlachaki E, Samiotaki M, Laspa D, Theodoridou S, Tsiftsoglou AS, Papadopoulou LC. Miliotou AN, et al. Among authors: tsiftsoglou as. J Biol Res (Thessalon). 2021 Jul 20;28(1):16. doi: 10.1186/s40709-021-00148-3. J Biol Res (Thessalon). 2021. PMID: 34284828 Free PMC article.
102 results