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An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.
Westberg M, Su Y, Zou X, Huang P, Rustagi A, Garhyan J, Patel PB, Fernandez D, Wu Y, Hao C, Lo CW, Karim M, Ning L, Beck A, Saenkham-Huntsinger P, Tat V, Drelich A, Peng BH, Einav S, Tseng CK, Blish C, Lin MZ. Westberg M, et al. Among authors: tseng ck. Sci Transl Med. 2024 Mar 13;16(738):eadi0979. doi: 10.1126/scitranslmed.adi0979. Epub 2024 Mar 13. Sci Transl Med. 2024. PMID: 38478629
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Yang KS, Ma XR, Ma Y, Alugubelli YR, Scott DA, Vatansever EC, Drelich AK, Sankaran B, Geng ZZ, Blankenship LR, Ward HE, Sheng YJ, Hsu JC, Kratch KC, Zhao B, Hayatshahi HS, Liu J, Li P, Fierke CA, Tseng CK, Xu S, Liu WR. Yang KS, et al. Among authors: tseng ck. ChemMedChem. 2021 Mar 18;16(6):942-948. doi: 10.1002/cmdc.202000924. Epub 2020 Dec 10. ChemMedChem. 2021. PMID: 33283984 Free PMC article.
Bepridil is potent against SARS-CoV-2 in vitro.
Vatansever EC, Yang KS, Drelich AK, Kratch KC, Cho CC, Kempaiah KR, Hsu JC, Mellott DM, Xu S, Tseng CK, Liu WR. Vatansever EC, et al. Among authors: tseng ck. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2012201118. doi: 10.1073/pnas.2012201118. Proc Natl Acad Sci U S A. 2021. PMID: 33597253 Free PMC article.
Efficacy and self-similarity of SARS-CoV-2 thermal decontamination.
Yap TF, Hsu JC, Liu Z, Rayavara K, Tat V, Tseng CK, Preston DJ. Yap TF, et al. Among authors: tseng ck. J Hazard Mater. 2022 May 5;429:127709. doi: 10.1016/j.jhazmat.2021.127709. Epub 2021 Nov 7. J Hazard Mater. 2022. PMID: 35086724 Free PMC article.
Bepridil is potent against SARS-CoV-2 In Vitro.
Vatansever EC, Yang K, Kratch KC, Drelich A, Cho CC, Mellott DM, Xu S, Tseng CK, Liu WR. Vatansever EC, et al. Among authors: tseng ck. bioRxiv [Preprint]. 2020 Jul 27:2020.05.23.112235. doi: 10.1101/2020.05.23.112235. bioRxiv. 2020. PMID: 32511370 Free PMC article. Updated. Preprint.
A novel receptor-binding domain (RBD)-based mRNA vaccine against SARS-CoV-2.
Tai W, Zhang X, Drelich A, Shi J, Hsu JC, Luchsinger L, Hillyer CD, Tseng CK, Jiang S, Du L. Tai W, et al. Among authors: tseng ck. Cell Res. 2020 Oct;30(10):932-935. doi: 10.1038/s41422-020-0387-5. Epub 2020 Aug 5. Cell Res. 2020. PMID: 32759966 Free PMC article. No abstract available.
283 results