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Patient-derived xenograft mouse models to investigate tropism to the central nervous system and retina of primary and secondary central nervous system lymphoma.
Isbell LK, Tschuch C, Doostkam S, Waldeck S, Andrieux G, Shoumariyeh K, Lenhard D, Schaefer HE, Reinacher PC, Bartsch I, Pantic M, Vinnakota JM, Kakkassery V, Schorb E, Scherer F, Frey AV, Boerries M, Illerhaus G, Duyster J, Schueler J, von Bubnoff N. Isbell LK, et al. Among authors: tschuch c. Neuropathol Appl Neurobiol. 2023 Apr;49(2):e12899. doi: 10.1111/nan.12899. Neuropathol Appl Neurobiol. 2023. PMID: 36879456
CXCR4, CXCR5 and CD44 May Be Involved in Homing of Lymphoma Cells into the Eye in a Patient Derived Xenograft Homing Mouse Model for Primary Vitreoretinal Lymphoma.
Babst N, Isbell LK, Rommel F, Tura A, Ranjbar M, Grisanti S, Tschuch C, Schueler J, Doostkam S, Reinacher PC, Duyster J, Kakkassery V, von Bubnoff N. Babst N, et al. Among authors: tschuch c. Int J Mol Sci. 2022 Oct 4;23(19):11757. doi: 10.3390/ijms231911757. Int J Mol Sci. 2022. PMID: 36233057 Free PMC article.
Off-target effects of siRNA specific for GFP.
Tschuch C, Schulz A, Pscherer A, Werft W, Benner A, Hotz-Wagenblatt A, Barrionuevo LS, Lichter P, Mertens D. Tschuch C, et al. BMC Mol Biol. 2008 Jun 24;9:60. doi: 10.1186/1471-2199-9-60. BMC Mol Biol. 2008. PMID: 18577207 Free PMC article.
Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.
Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M, Caudron-Herger M, Oakes C, Fleig V, Keklikoglou I, Allegra D, Serra L, Thakurela S, Tiwari V, Weichenhan D, Benner A, Radlwimmer B, Zentgraf H, Wiemann S, Rippe K, Plass C, Döhner H, Lichter P, Stilgenbauer S, Mertens D. Garding A, et al. Among authors: tschuch c. PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4. PLoS Genet. 2013. PMID: 23593011 Free PMC article.
Chronic lymphocytic leukemia and 13q14: miRs and more.
Mertens D, Philippen A, Ruppel M, Allegra D, Bhattacharya N, Tschuch C, Wolf S, Idler I, Zenz T, Stilgenbauer S. Mertens D, et al. Among authors: tschuch c. Leuk Lymphoma. 2009 Mar;50(3):502-5. doi: 10.1080/10428190902763509. Leuk Lymphoma. 2009. PMID: 19347735
Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum.
Le Saux O, Urban Z, Tschuch C, Csiszar K, Bacchelli B, Quaglino D, Pasquali-Ronchetti I, Pope FM, Richards A, Terry S, Bercovitch L, de Paepe A, Boyd CD. Le Saux O, et al. Among authors: tschuch c. Nat Genet. 2000 Jun;25(2):223-7. doi: 10.1038/76102. Nat Genet. 2000. PMID: 10835642