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The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL.
Humbert M, Federzoni EA, Britschgi A, Schläfli AM, Valk PJ, Kaufmann T, Haferlach T, Behre G, Simon HU, Torbett BE, Fey MF, Tschan MP. Humbert M, et al. Among authors: tschan mp. J Leukoc Biol. 2014 Jan;95(1):83-93. doi: 10.1189/jlb.1112608. Epub 2013 Sep 13. J Leukoc Biol. 2014. PMID: 24038216 Free PMC article.
Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients.
Helbling M, Lukesch A, Haimovici A, Karamitopoulou E, Berger MD, Hädrich M, Mallaev M, Schnüriger B, Koelzer VH, Dawson H, Borner M, Langer R, Rosenberg R, Nitsche U, Inderbitzin D, Lugli A, Tschan M, Zlobec I. Helbling M, et al. Oncotarget. 2014 Jul 15;5(13):4671-82. doi: 10.18632/oncotarget.2069. Oncotarget. 2014. PMID: 25015728 Free PMC article.
p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells.
Trocoli A, Bensadoun P, Richard E, Labrunie G, Merhi F, Schläfli AM, Brigger D, Souquere S, Pierron G, Pasquet JM, Soubeyran P, Reiffers J, Ségal-Bendirdjian E, Tschan MP, Djavaheri-Mergny M. Trocoli A, et al. Among authors: tschan mp. Cell Death Differ. 2014 Dec;21(12):1852-61. doi: 10.1038/cdd.2014.102. Epub 2014 Jul 18. Cell Death Differ. 2014. PMID: 25034783 Free PMC article.
115 results