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Hypothalamic astrocytes control systemic glucose metabolism and energy balance.
Herrera Moro Chao D, Kirchner MK, Pham C, Foppen E, Denis RGP, Castel J, Morel C, Montalban E, Hassouna R, Bui LC, Renault J, Mouffle C, García-Cáceres C, Tschöp MH, Li D, Martin C, Stern JE, Luquet SH. Herrera Moro Chao D, et al. Among authors: tschop mh. Cell Metab. 2022 Oct 4;34(10):1532-1547.e6. doi: 10.1016/j.cmet.2022.09.002. Cell Metab. 2022. PMID: 36198294 Free PMC article.
A role for astrocytes in the central control of metabolism.
Yi CX, Habegger KM, Chowen JA, Stern J, Tschöp MH. Yi CX, et al. Among authors: tschop mh. Neuroendocrinology. 2011;93(3):143-9. doi: 10.1159/000324888. Epub 2011 Mar 4. Neuroendocrinology. 2011. PMID: 21372559 Review.
Targeted estrogen delivery reverses the metabolic syndrome.
Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, Irmler M, Beckers J, de Angelis MH, Tiano JP, Mauvais-Jarvis F, Perez-Tilve D, Pfluger P, Zhang L, Gelfanov V, DiMarchi RD, Tschöp MH. Finan B, et al. Among authors: tschop mh. Nat Med. 2012 Dec;18(12):1847-56. doi: 10.1038/nm.3009. Epub 2012 Nov 11. Nat Med. 2012. PMID: 23142820 Free PMC article.
Hypothalamic astrocytes in obesity.
García-Cáceres C, Yi CX, Tschöp MH. García-Cáceres C, et al. Among authors: tschop mh. Endocrinol Metab Clin North Am. 2013 Mar;42(1):57-66. doi: 10.1016/j.ecl.2012.11.003. Epub 2012 Dec 12. Endocrinol Metab Clin North Am. 2013. PMID: 23391239 Review.
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.
Müller TD, Müller A, Yi CX, Habegger KM, Meyer CW, Gaylinn BD, Finan B, Heppner K, Trivedi C, Bielohuby M, Abplanalp W, Meyer F, Piechowski CL, Pratzka J, Stemmer K, Holland J, Hembree J, Bhardwaj N, Raver C, Ottaway N, Krishna R, Sah R, Sallee FR, Woods SC, Perez-Tilve D, Bidlingmaier M, Thorner MO, Krude H, Smiley D, DiMarchi R, Hofmann S, Pfluger PT, Kleinau G, Biebermann H, Tschöp MH. Müller TD, et al. Among authors: tschop mh. Nat Commun. 2013;4:1968. doi: 10.1038/ncomms2968. Nat Commun. 2013. PMID: 23744028 Free PMC article.
High calorie diet triggers hypothalamic angiopathy.
Yi CX, Gericke M, Krüger M, Alkemade A, Kabra DG, Hanske S, Filosa J, Pfluger P, Bingham N, Woods SC, Herman J, Kalsbeek A, Baumann M, Lang R, Stern JE, Bechmann I, Tschöp MH. Yi CX, et al. Among authors: tschop mh. Mol Metab. 2012 Aug 9;1(1-2):95-100. doi: 10.1016/j.molmet.2012.08.004. eCollection 2012. Mol Metab. 2012. PMID: 24024123 Free PMC article.
Hormones and diet, but not body weight, control hypothalamic microglial activity.
Gao Y, Ottaway N, Schriever SC, Legutko B, García-Cáceres C, de la Fuente E, Mergen C, Bour S, Thaler JP, Seeley RJ, Filosa J, Stern JE, Perez-Tilve D, Schwartz MW, Tschöp MH, Yi CX. Gao Y, et al. Among authors: tschop mh. Glia. 2014 Jan;62(1):17-25. doi: 10.1002/glia.22580. Epub 2013 Oct 28. Glia. 2014. PMID: 24166765 Free PMC article.
The emerging neurobiology of calorie addiction.
García-Cáceres C, Tschöp MH. García-Cáceres C, et al. Among authors: tschop mh. Elife. 2014;3:e01928. doi: 10.7554/eLife.01928. Epub 2014 Jan 7. Elife. 2014. PMID: 24399459 Free PMC article.
430 results