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431 results

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Page 1
Anti-obesity drug discovery: advances and challenges.
Müller TD, Blüher M, Tschöp MH, DiMarchi RD. Müller TD, et al. Among authors: tschop mh. Nat Rev Drug Discov. 2022 Mar;21(3):201-223. doi: 10.1038/s41573-021-00337-8. Epub 2021 Nov 23. Nat Rev Drug Discov. 2022. PMID: 34815532 Free PMC article. Review.
Effects of obestatin on energy balance and growth hormone secretion in rodents.
Nogueiras R, Pfluger P, Tovar S, Arnold M, Mitchell S, Morris A, Perez-Tilve D, Vázquez MJ, Wiedmer P, Castañeda TR, DiMarchi R, Tschöp M, Schurmann A, Joost HG, Williams LM, Langhans W, Diéguez C. Nogueiras R, et al. Endocrinology. 2007 Jan;148(1):21-6. doi: 10.1210/en.2006-0915. Epub 2006 Sep 28. Endocrinology. 2007. PMID: 17008393
Coupled with uncouplers: the curious case of lifespan.
Lockie SH, Müller TD, Tschöp MH. Lockie SH, et al. Among authors: tschop mh. Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E619-20. doi: 10.1152/ajpendo.00060.2009. Epub 2009 Feb 10. Am J Physiol Endocrinol Metab. 2009. PMID: 19208859 Free article. No abstract available.
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
Nogueiras R, Pérez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, López M, Woods SC, DiMarchi R, Diéguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH. Nogueiras R, et al. Among authors: tschop mh. J Neurosci. 2009 May 6;29(18):5916-25. doi: 10.1523/JNEUROSCI.5977-08.2009. J Neurosci. 2009. PMID: 19420258 Free PMC article.
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents.
Day JW, Ottaway N, Patterson JT, Gelfanov V, Smiley D, Gidda J, Findeisen H, Bruemmer D, Drucker DJ, Chaudhary N, Holland J, Hembree J, Abplanalp W, Grant E, Ruehl J, Wilson H, Kirchner H, Lockie SH, Hofmann S, Woods SC, Nogueiras R, Pfluger PT, Perez-Tilve D, DiMarchi R, Tschöp MH. Day JW, et al. Among authors: tschop mh. Nat Chem Biol. 2009 Oct;5(10):749-57. doi: 10.1038/nchembio.209. Epub 2009 Jul 13. Nat Chem Biol. 2009. PMID: 19597507
The 1D1 of burning calories.
Müller TD, Chaudhary N, Pfluger PT, Tschöp M. Müller TD, et al. Obes Facts. 2008;1(5):223-6. doi: 10.1159/000164881. Epub 2008 Oct 23. Obes Facts. 2008. PMID: 20054182 Free PMC article. No abstract available.
Glucagon regulation of energy metabolism.
Heppner KM, Habegger KM, Day J, Pfluger PT, Perez-Tilve D, Ward B, Gelfanov V, Woods SC, DiMarchi R, Tschöp M. Heppner KM, et al. Physiol Behav. 2010 Jul 14;100(5):545-8. doi: 10.1016/j.physbeh.2010.03.019. Epub 2010 Apr 8. Physiol Behav. 2010. PMID: 20381509 Review.
Melanocortin signaling in the CNS directly regulates circulating cholesterol.
Perez-Tilve D, Hofmann SM, Basford J, Nogueiras R, Pfluger PT, Patterson JT, Grant E, Wilson-Perez HE, Granholm NA, Arnold M, Trevaskis JL, Butler AA, Davidson WS, Woods SC, Benoit SC, Sleeman MW, DiMarchi RD, Hui DY, Tschöp MH. Perez-Tilve D, et al. Among authors: tschop mh. Nat Neurosci. 2010 Jul;13(7):877-82. doi: 10.1038/nn.2569. Epub 2010 Jun 6. Nat Neurosci. 2010. PMID: 20526334 Free PMC article.
Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein.
Bielohuby M, Menhofer D, Kirchner H, Stoehr BJ, Müller TD, Stock P, Hempel M, Stemmer K, Pfluger PT, Kienzle E, Christ B, Tschöp MH, Bidlingmaier M. Bielohuby M, et al. Among authors: tschop mh. Am J Physiol Endocrinol Metab. 2011 Jan;300(1):E65-76. doi: 10.1152/ajpendo.00478.2010. Epub 2010 Oct 13. Am J Physiol Endocrinol Metab. 2011. PMID: 20943751 Free article.
431 results