Tsantrizos YS - Search Results

1

Asymmetric Library Synthesis of P-Chiral t-Butyl-Substituted Secondary and Tertiary Phosphine Oxides.

Li SG, Yuan M, Topic F, Han ZS, Senanayake CH, Tsantrizos YS. Li SG, et al. Among authors: tsantrizos ys. J Org Chem. 2019 Jun 7;84(11):7291-7302. doi: 10.1021/acs.joc.9b00945. Epub 2019 May 29. J Org Chem. 2019. PMID: 31099249

2

A highly concise and convergent synthesis of HCV polymerase inhibitor Deleobuvir (BI 207127): application of a one-pot borylation-Suzuki coupling reaction.

Zhang Y, Lu BZ, Li G, Rodriguez S, Tan J, Wei HX, Liu J, Roschangar F, Ding F, Zhao W, Qu B, Reeves D, Grinberg N, Lee H, Heckmann G, Niemeier O, Brenner M, Tsantrizos Y, Beaulieu PL, Hossain A, Yee N, Farina V, Senanayake CH. Zhang Y, et al. Org Lett. 2014 Sep 5;16(17):4558-61. doi: 10.1021/ol5021114. Epub 2014 Aug 8. Org Lett. 2014. PMID: 25105303

3

Concise and Practical Asymmetric Synthesis of a Challenging Atropisomeric HIV Integrase Inhibitor.

Fandrick KR, Li W, Zhang Y, Tang W, Gao J, Rodriguez S, Patel ND, Reeves DC, Wu JP, Sanyal S, Gonnella N, Qu B, Haddad N, Lorenz JC, Sidhu K, Wang J, Ma S, Grinberg N, Lee H, Tsantrizos Y, Poupart MA, Busacca CA, Yee NK, Lu BZ, Senanayake CH. Fandrick KR, et al. Angew Chem Int Ed Engl. 2015 Jun 8;54(24):7144-8. doi: 10.1002/anie.201501575. Epub 2015 May 4. Angew Chem Int Ed Engl. 2015. PMID: 25939331

4

Metal-Free Cycloetherification by in Situ Generated P-Stereogenic α-Diazanium Intermediates: A Convergent Synthesis of Enantiomerically Pure Dihydrobenzooxaphospholes.

Li SG, Han ZS, Viereck P, Lee H, Kurouski D, Senanayake CH, Tsantrizos YS. Li SG, et al. Among authors: tsantrizos ys. Org Lett. 2017 Feb 17;19(4):894-897. doi: 10.1021/acs.orglett.7b00051. Epub 2017 Feb 3. Org Lett. 2017. PMID: 28155279 Free PMC article.

5

P-Chiral, N-phosphoryl sulfonamide Brønsted acids with an intramolecular hydrogen bond interaction that modulates organocatalysis.

Yuan M, Mbaezue II, Zhou Z, Topic F, Tsantrizos YS. Yuan M, et al. Among authors: tsantrizos ys. Org Biomol Chem. 2019 Oct 14;17(38):8690-8694. doi: 10.1039/c9ob01774g. Epub 2019 Sep 19. Org Biomol Chem. 2019. PMID: 31535120

6

Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS).

Feng Y, Park J, Li SG, Boutin R, Viereck P, Schilling MA, Berghuis AM, Tsantrizos YS. Feng Y, et al. Among authors: tsantrizos ys. J Med Chem. 2019 Nov 14;62(21):9691-9702. doi: 10.1021/acs.jmedchem.9b01104. Epub 2019 Oct 16. J Med Chem. 2019. PMID: 31577901

7

Backbone modifications of aromatic peptide nucleic acid (APNA ) monomers and their hybridization properties with DNA and RNA.

Fader LD, Boyd M, Tsantrizos YS. Fader LD, et al. Among authors: tsantrizos ys. J Org Chem. 2001 May 18;66(10):3372-9. doi: 10.1021/jo001650o. J Org Chem. 2001. PMID: 11348119

8

Solid-phase synthesis of peptidomimetic inhibitors for the hepatitis C virus NS3 protease.

Poupart MA, Cameron DR, Chabot C, Ghiro E, Goudreau N, Goulet S, Poirier M, Tsantrizos YS. Poupart MA, et al. Among authors: tsantrizos ys. J Org Chem. 2001 Jul 13;66(14):4743-51. doi: 10.1021/jo010164d. J Org Chem. 2001. PMID: 11442398

9

Studies on the Biosynthesis of the Fungal Metabolite Oudenone. 2. Synthesis and Enzymatic Cyclization of an alpha-Diketone, Open-Chain Precursor into Oudenone in Cultures of Oudemansiella radicata.

Tsantrizos YS, Yang X, McClory A. Tsantrizos YS, et al. J Org Chem. 1999 Sep 3;64(18):6609-6614. doi: 10.1021/jo9901135. J Org Chem. 1999. PMID: 11674663

10

Potent inhibitors of the hepatitis C virus NS3 protease: design and synthesis of macrocyclic substrate-based beta-strand mimics.

Goudreau N, Brochu C, Cameron DR, Duceppe JS, Faucher AM, Ferland JM, Grand-Maître C, Poirier M, Simoneau B, Tsantrizos YS. Goudreau N, et al. Among authors: tsantrizos ys. J Org Chem. 2004 Sep 17;69(19):6185-201. doi: 10.1021/jo049288r. J Org Chem. 2004. PMID: 15357576

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