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Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis.
Yang SM, Chan YL, Hua KF, Chang JM, Chen HL, Tsai YJ, Hsu YJ, Chao LK, Feng-Ling Y, Tsai YL, Wu SH, Wang YF, Tsai CL, Chen A, Ka SM. Yang SM, et al. Among authors: tsai cl, tsai yl, tsai yj. Free Radic Biol Med. 2014 Aug;73:260-9. doi: 10.1016/j.freeradbiomed.2014.05.009. Epub 2014 May 22. Free Radic Biol Med. 2014. PMID: 24858719
Cf-02, a novel benzamide-linked small molecule, blunts NF-κB activation and NLRP3 inflammasome assembly and improves acute onset of accelerated and severe lupus nephritis in mice.
Yang SR, Hua KF, Yang CY, Chen A, Weng JC, Tsai YL, Wan CJ, Wu CY, Lee CC, Chan JF, Hsieh CY, Hsu YJ, Wu CC, Mukhopadhyay D, Huang HS, Liu FC, Ka SM. Yang SR, et al. Among authors: tsai yl. FASEB J. 2021 Aug;35(8):e21785. doi: 10.1096/fj.202100047R. FASEB J. 2021. PMID: 34314075 Free PMC article.
493 results