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Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function.
Tay HG, Andre H, Chrysostomou V, Adusumalli S, Guo J, Ren X, Tan WS, Tor JE, Moreno-Moral A, Plastino F, Bartuma H, Cai Z, Tun SBB, Barathi VA, Siew Wei GT, Grenci G, Chong LY, Holmgren A, Kvanta A, Crowston JG, Petretto E, Tryggvason K. Tay HG, et al. Among authors: tryggvason k. Mol Ther. 2023 Mar 1;31(3):825-846. doi: 10.1016/j.ymthe.2022.12.012. Epub 2023 Jan 12. Mol Ther. 2023. PMID: 36638800 Free PMC article.
Periportal macrophages protect against commensal-driven liver inflammation.
Miyamoto Y, Kikuta J, Matsui T, Hasegawa T, Fujii K, Okuzaki D, Liu YC, Yoshioka T, Seno S, Motooka D, Uchida Y, Yamashita E, Kobayashi S, Eguchi H, Morii E, Tryggvason K, Shichita T, Kayama H, Atarashi K, Kunisawa J, Honda K, Takeda K, Ishii M. Miyamoto Y, et al. Among authors: tryggvason k. Nature. 2024 Apr 24. doi: 10.1038/s41586-024-07372-6. Online ahead of print. Nature. 2024. PMID: 38658756
Skin mesenchymal niches maintain and protect AML-initiating stem cells.
Sandhow L, Cai H, Leonard E, Xiao P, Tomaipitinca L, Månsson A, Kondo M, Sun X, Johansson AS, Tryggvason K, Kasper M, Järås M, Qian H. Sandhow L, et al. Among authors: tryggvason k. J Exp Med. 2023 Oct 2;220(10):e20220953. doi: 10.1084/jem.20220953. Epub 2023 Jul 26. J Exp Med. 2023. PMID: 37516911 Free PMC article.
Viral proteases activate the CARD8 inflammasome in the human cardiovascular system.
Nadkarni R, Chu WC, Lee CQE, Mohamud Y, Yap L, Toh GA, Beh S, Lim R, Fan YM, Zhang YL, Robinson K, Tryggvason K, Luo H, Zhong F, Ho L. Nadkarni R, et al. Among authors: tryggvason k. J Exp Med. 2022 Oct 3;219(10):e20212117. doi: 10.1084/jem.20212117. Epub 2022 Sep 21. J Exp Med. 2022. PMID: 36129453 Free PMC article.
A high-resolution map of human RNA translation.
Chothani SP, Adami E, Widjaja AA, Langley SR, Viswanathan S, Pua CJ, Zhihao NT, Harmston N, D'Agostino G, Whiffin N, Mao W, Ouyang JF, Lim WW, Lim S, Lee CQE, Grubman A, Chen J, Kovalik JP, Tryggvason K, Polo JM, Ho L, Cook SA, Rackham OJL, Schafer S. Chothani SP, et al. Among authors: tryggvason k. Mol Cell. 2022 Aug 4;82(15):2885-2899.e8. doi: 10.1016/j.molcel.2022.06.023. Epub 2022 Jul 15. Mol Cell. 2022. PMID: 35841888 Free article.
Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis.
Tanoue A, Katayama K, Ito Y, Joh K, Toda M, Yasuma T, D'Alessandro-Gabazza CN, Kawachi H, Yan K, Ito M, Gabazza EC, Tryggvason K, Dohi K. Tanoue A, et al. Among authors: tryggvason k. Sci Rep. 2021 Oct 15;11(1):20556. doi: 10.1038/s41598-021-00159-z. Sci Rep. 2021. PMID: 34654837 Free PMC article.
426 results