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Obestatin: is it really doing something?
Trovato L, Gallo D, Settanni F, Gesmundo I, Ghigo E, Granata R. Trovato L, et al. Front Horm Res. 2014;42:175-85. doi: 10.1159/000358346. Epub 2014 Apr 7. Front Horm Res. 2014. PMID: 24732935 Review.
Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.
Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E. Granata R, et al. Among authors: trovato l. Diabetes. 2008 Apr;57(4):967-79. doi: 10.2337/db07-1104. Epub 2007 Dec 27. Diabetes. 2008. PMID: 18162507
The role of obestatin in glucose and lipid metabolism.
Gargantini E, Grande C, Trovato L, Ghigo E, Granata R. Gargantini E, et al. Among authors: trovato l. Horm Metab Res. 2013 Dec;45(13):1002-8. doi: 10.1055/s-0033-1351325. Epub 2013 Aug 15. Horm Metab Res. 2013. PMID: 23950037 Review.
Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic beta-cells and human islets: involvement of 3',5'-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-Kinase/Akt signaling.
Granata R, Settanni F, Biancone L, Trovato L, Nano R, Bertuzzi F, Destefanis S, Annunziata M, Martinetti M, Catapano F, Ghè C, Isgaard J, Papotti M, Ghigo E, Muccioli G. Granata R, et al. Among authors: trovato l. Endocrinology. 2007 Feb;148(2):512-29. doi: 10.1210/en.2006-0266. Epub 2006 Oct 26. Endocrinology. 2007. PMID: 17068144
RFamide peptides 43RFa and 26RFa both promote survival of pancreatic β-cells and human pancreatic islets but exert opposite effects on insulin secretion.
Granata R, Settanni F, Trovato L, Gallo D, Gesmundo I, Nano R, Gallo MP, Bergandi L, Volante M, Alloatti G, Piemonti L, Leprince J, Papotti M, Vaudry H, Ong H, Ghigo E. Granata R, et al. Among authors: trovato l. Diabetes. 2014 Jul;63(7):2380-93. doi: 10.2337/db13-1522. Epub 2014 Mar 12. Diabetes. 2014. PMID: 24622796 Free article.
Growth hormone-releasing hormone promotes survival of cardiac myocytes in vitro and protects against ischaemia-reperfusion injury in rat heart.
Granata R, Trovato L, Gallo MP, Destefanis S, Settanni F, Scarlatti F, Brero A, Ramella R, Volante M, Isgaard J, Levi R, Papotti M, Alloatti G, Ghigo E. Granata R, et al. Among authors: trovato l. Cardiovasc Res. 2009 Jul 15;83(2):303-12. doi: 10.1093/cvr/cvp090. Epub 2009 Mar 17. Cardiovasc Res. 2009. PMID: 19293247 Free article.
74 results