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Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Kumar R, Milanesi S, Szpakowska M, Dotta L, Di Silvestre D, Trotta AM, Bello AM, Giacomelli M, Benedito M, Azevedo J, Pereira A, Cortesao E, Vacchini A, Castagna A, Pinelli M, Moratto D, Bonecchi R, Locati M, Scala S, Chevigné A, Borroni EM, Badolato R. Kumar R, et al. Among authors: trotta am. JCI Insight. 2023 Mar 8;8(5):e145688. doi: 10.1172/jci.insight.145688. JCI Insight. 2023. PMID: 36883568 Free PMC article.
Predictive immune biomarkers: an unattainable chimera?
Trotta AM, Pacelli R, Scala S. Trotta AM, et al. Cell Mol Immunol. 2018 Aug;15(8):740-742. doi: 10.1038/cmi.2017.162. Epub 2018 Feb 5. Cell Mol Immunol. 2018. PMID: 29400708 Free PMC article. No abstract available.
Hepatocellular carcinoma (HCC) tumor microenvironment is more suppressive than colorectal cancer liver metastasis (CRLM) tumor microenvironment.
Santagata S, Rea G, Castaldo D, Napolitano M, Capiluongo A, D'Alterio C, Trotta AM, Ieranò C, Portella L, Di Maro S, Tatangelo F, Albino V, Guarino R, Cutolo C, Izzo F, Scala S. Santagata S, et al. Among authors: trotta am. Hepatol Int. 2024 Apr;18(2):568-581. doi: 10.1007/s12072-023-10537-6. Epub 2023 May 4. Hepatol Int. 2024. PMID: 37142825 Free PMC article.
Targeting CXCR4 impaired T regulatory function through PTEN in renal cancer patients.
Santagata S, Rea G, Bello AM, Capiluongo A, Napolitano M, Desicato S, Fragale A, D'Alterio C, Trotta AM, Ieranò C, Portella L, Persico F, Di Napoli M, Di Maro S, Feroce F, Azzaro R, Gabriele L, Longo N, Pignata S, Perdonà S, Scala S. Santagata S, et al. Among authors: trotta am. Br J Cancer. 2024 May 4. doi: 10.1038/s41416-024-02702-x. Online ahead of print. Br J Cancer. 2024. PMID: 38704478
Regulatory T cells, interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), CXCL10, CXCL11, epidermal growth factor (EGF) and hepatocyte growth factor (HGF) as surrogate markers of host immunity in patients with renal cell carcinoma.
Polimeno M, Napolitano M, Costantini S, Portella L, Esposito A, Capone F, Guerriero E, Trotta A, Zanotta S, Pucci L, Longo N, Perdonà S, Pignata S, Castello G, Scala S. Polimeno M, et al. BJU Int. 2013 Sep;112(5):686-96. doi: 10.1111/bju.12068. Epub 2013 Mar 15. BJU Int. 2013. PMID: 23495770
Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients.
Napolitano M, D'Alterio C, Cardone E, Trotta AM, Pecori B, Rega D, Pace U, Scala D, Scognamiglio G, Tatangelo F, Cacciapuoti C, Pacelli R, Delrio P, Scala S. Napolitano M, et al. Among authors: trotta am. Oncotarget. 2015 Apr 10;6(10):8261-70. doi: 10.18632/oncotarget.3014. Oncotarget. 2015. PMID: 25823653 Free PMC article.
31 results