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B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.
Milillo MA, Velásquez LN, Trotta A, Delpino MV, Marinho FV, Balboa L, Vermeulen M, Espindola SL, Rodriguez-Rodrigues N, Fernández GC, Oliveira SC, Giambartolomei GH, Barrionuevo P. Milillo MA, et al. Among authors: trotta a. PLoS Pathog. 2017 Aug 2;13(8):e1006527. doi: 10.1371/journal.ppat.1006527. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28767704 Free PMC article.
Brucella abortus-infected platelets modulate the activation of neutrophils.
Trotta A, Milillo MA, Serafino A, Castillo LA, Birnberg Weiss F, Delpino MV, Giambartolomei GH, Fernández GC, Barrionuevo P. Trotta A, et al. Immunol Cell Biol. 2020 Oct;98(9):743-756. doi: 10.1111/imcb.12373. Epub 2020 Aug 4. Immunol Cell Biol. 2020. PMID: 32623755
Brucella abortus RNA does not polarize macrophages to a particular profile but interferes with M1 polarization.
Serafino A, Marin Franco JL, Maio M, Trotta A, Genoula M, Castillo LA, Birnberg Weiss F, Pittaluga JR, Balboa L, Barrionuevo P, Milillo MA. Serafino A, et al. Among authors: trotta a. PLoS Negl Trop Dis. 2022 Nov 28;16(11):e0010950. doi: 10.1371/journal.pntd.0010950. eCollection 2022 Nov. PLoS Negl Trop Dis. 2022. PMID: 36441810 Free PMC article.
Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation.
Sierra JM, Secchiari F, Nuñez SY, Iraolagoitia XLR, Ziblat A, Friedrich AD, Regge MV, Santilli MC, Torres NI, Gantov M, Trotta A, Ameri C, Vitagliano G, Pita HR, Rico L, Rovegno A, Richards N, Domaica CI, Zwirner NW, Fuertes MB. Sierra JM, et al. Among authors: trotta a. Front Immunol. 2021 Sep 20;12:745939. doi: 10.3389/fimmu.2021.745939. eCollection 2021. Front Immunol. 2021. PMID: 34616407 Free PMC article.
231 results