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Advances in high-throughput mass spectrometry in drug discovery.
Dueñas ME, Peltier-Heap RE, Leveridge M, Annan RS, Büttner FH, Trost M. Dueñas ME, et al. Among authors: trost m. EMBO Mol Med. 2023 Jan 11;15(1):e14850. doi: 10.15252/emmm.202114850. Epub 2022 Dec 14. EMBO Mol Med. 2023. PMID: 36515561 Free PMC article. Review.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2.
Hatton CF, Botting RA, Dueñas ME, Haq IJ, Verdon B, Thompson BJ, Spegarova JS, Gothe F, Stephenson E, Gardner AI, Murphy S, Scott J, Garnett JP, Carrie S, Powell J, Khan CMA, Huang L, Hussain R, Coxhead J, Davey T, Simpson AJ, Haniffa M, Hambleton S, Brodlie M, Ward C, Trost M, Reynolds G, Duncan CJA. Hatton CF, et al. Among authors: trost m. Nat Commun. 2021 Dec 7;12(1):7092. doi: 10.1038/s41467-021-27318-0. Nat Commun. 2021. PMID: 34876592 Free PMC article.
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia.
Marín-Rubio JL, Peltier-Heap RE, Dueñas ME, Heunis T, Dannoura A, Inns J, Scott J, Simpson AJ, Blair HJ, Heidenreich O, Allan JM, Watt JE, Martin MP, Saxty B, Trost M. Marín-Rubio JL, et al. Among authors: trost m. J Med Chem. 2022 Sep 22;65(18):12014-12030. doi: 10.1021/acs.jmedchem.2c00671. Epub 2022 Sep 12. J Med Chem. 2022. PMID: 36094045 Free PMC article.
Mass spectrometry techniques for studying the ubiquitin system.
Heap RE, Gant MS, Lamoliatte F, Peltier J, Trost M. Heap RE, et al. Among authors: trost m. Biochem Soc Trans. 2017 Oct 15;45(5):1137-1148. doi: 10.1042/BST20170091. Epub 2017 Sep 22. Biochem Soc Trans. 2017. PMID: 28939693 Review.
LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages.
Härtlova A, Herbst S, Peltier J, Rodgers A, Bilkei-Gorzo O, Fearns A, Dill BD, Lee H, Flynn R, Cowley SA, Davies P, Lewis PA, Ganley IG, Martinez J, Alessi DR, Reith AD, Trost M, Gutierrez MG. Härtlova A, et al. Among authors: trost m. EMBO J. 2018 Jun 15;37(12):e98694. doi: 10.15252/embj.201798694. Epub 2018 May 22. EMBO J. 2018. PMID: 29789389 Free PMC article.
261 results