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An ERK5-KLF2 signalling module regulates early embryonic gene expression and telomere rejuvenation in stem cells.
Brown HA, Williams CAC, Zhou H, Rios-Szwed D, Fernandez-Alonso R, Mansoor S, McMulkin L, Toth R, Gourlay R, Peltier J, Dieguez-Martinez N, Trost M, Lizcano JM, Stavridis MP, Findlay GM. Brown HA, et al. Among authors: trost m. Biochem J. 2021 Dec 10;478(23):4119-4136. doi: 10.1042/BCJ20210646. Biochem J. 2021. PMID: 34780645 Free PMC article.
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
Kazlauskaite A, Kondapalli C, Gourlay R, Campbell DG, Ritorto MS, Hofmann K, Alessi DR, Knebel A, Trost M, Muqit MM. Kazlauskaite A, et al. Among authors: trost m. Biochem J. 2014 May 15;460(1):127-39. doi: 10.1042/BJ20140334. Biochem J. 2014. PMID: 24660806 Free PMC article.
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
Kazlauskaite A, Martínez-Torres RJ, Wilkie S, Kumar A, Peltier J, Gonzalez A, Johnson C, Zhang J, Hope AG, Peggie M, Trost M, van Aalten DM, Alessi DR, Prescott AR, Knebel A, Walden H, Muqit MM. Kazlauskaite A, et al. Among authors: trost m. EMBO Rep. 2015 Aug;16(8):939-54. doi: 10.15252/embr.201540352. Epub 2015 Jun 25. EMBO Rep. 2015. PMID: 26116755 Free PMC article.
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.
Lai YC, Kondapalli C, Lehneck R, Procter JB, Dill BD, Woodroof HI, Gourlay R, Peggie M, Macartney TJ, Corti O, Corvol JC, Campbell DG, Itzen A, Trost M, Muqit MM. Lai YC, et al. Among authors: trost m. EMBO J. 2015 Nov 12;34(22):2840-61. doi: 10.15252/embj.201591593. Epub 2015 Oct 15. EMBO J. 2015. PMID: 26471730 Free PMC article.
A mutant O-GlcNAcase enriches Drosophila developmental regulators.
Selvan N, Williamson R, Mariappa D, Campbell DG, Gourlay R, Ferenbach AT, Aristotelous T, Hopkins-Navratilova I, Trost M, van Aalten DMF. Selvan N, et al. Among authors: trost m. Nat Chem Biol. 2017 Aug;13(8):882-887. doi: 10.1038/nchembio.2404. Epub 2017 Jun 12. Nat Chem Biol. 2017. PMID: 28604694 Free PMC article.
Mass spectrometry techniques for studying the ubiquitin system.
Heap RE, Gant MS, Lamoliatte F, Peltier J, Trost M. Heap RE, et al. Among authors: trost m. Biochem Soc Trans. 2017 Oct 15;45(5):1137-1148. doi: 10.1042/BST20170091. Epub 2017 Sep 22. Biochem Soc Trans. 2017. PMID: 28939693 Review.
261 results