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New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.
Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašič LP, Tomašič T. Durcik M, et al. Among authors: trontelj j. Eur J Med Chem. 2021 Mar 5;213:113200. doi: 10.1016/j.ejmech.2021.113200. Epub 2021 Jan 22. Eur J Med Chem. 2021. PMID: 33524686
Influence of metabolism on endocrine activities of bisphenol S.
Skledar DG, Schmidt J, Fic A, Klopčič I, Trontelj J, Dolenc MS, Finel M, Mašič LP. Skledar DG, et al. Among authors: trontelj j. Chemosphere. 2016 Aug;157:152-9. doi: 10.1016/j.chemosphere.2016.05.027. Epub 2016 May 21. Chemosphere. 2016. PMID: 27213244
The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.
Košak U, Brus B, Knez D, Žakelj S, Trontelj J, Pišlar A, Šink R, Jukič M, Živin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Sałat K, Colletier JP, Gobec S. Košak U, et al. Among authors: trontelj j. J Med Chem. 2018 Jan 11;61(1):119-139. doi: 10.1021/acs.jmedchem.7b01086. Epub 2017 Dec 22. J Med Chem. 2018. PMID: 29227101
Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.
Gobec M, Tomašič T, Štimac A, Frkanec R, Trontelj J, Anderluh M, Mlinarič-Raščan I, Jakopin Ž. Gobec M, et al. Among authors: trontelj j. J Med Chem. 2018 Apr 12;61(7):2707-2724. doi: 10.1021/acs.jmedchem.7b01052. Epub 2018 Mar 22. J Med Chem. 2018. PMID: 29543461
Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B.
Knez D, Colettis N, Iacovino LG, Sova M, Pišlar A, Konc J, Lešnik S, Higgs J, Kamecki F, Mangialavori I, Dolšak A, Žakelj S, Trontelj J, Kos J, Binda C, Marder M, Gobec S. Knez D, et al. Among authors: trontelj j. J Med Chem. 2020 Feb 13;63(3):1361-1387. doi: 10.1021/acs.jmedchem.9b01886. Epub 2020 Jan 22. J Med Chem. 2020. PMID: 31917923 Free PMC article.
132 results