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Novel tetrahydropyrido[1,2-a]isoindolone derivatives (valmerins): potent cyclin-dependent kinase/glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.
Boulahjar R, Ouach A, Matteo C, Bourg S, Ravache M, le Guével R, Marionneau S, Oullier T, Lozach O, Meijer L, Guguen-Guillouzo C, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: troin y. J Med Chem. 2012 Nov 26;55(22):9589-606. doi: 10.1021/jm3008536. Epub 2012 Nov 1. J Med Chem. 2012. PMID: 23083119
Efficient synthesis of β'-amino-α,β-unsaturated ketones.
Abrunhosa-Thomas I, Plas A, Kandepedu N, Chalard P, Troin Y. Abrunhosa-Thomas I, et al. Among authors: troin y. Beilstein J Org Chem. 2013;9:486-95. doi: 10.3762/bjoc.9.52. Epub 2013 Mar 6. Beilstein J Org Chem. 2013. PMID: 23504648 Free PMC article.
Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.
Boulahjar R, Ouach A, Bourg S, Bonnet P, Lozach O, Meijer L, Guguen-Guillouzo C, Le Guevel R, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Among authors: troin y. Eur J Med Chem. 2015 Aug 28;101:274-87. doi: 10.1016/j.ejmech.2015.06.046. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26142492 Free article.
In Vitro Anti-Inflammatory and Immunomodulatory Activities of an Extract from the Roots of Bupleurum rotundifolium.
Cholet J, Decombat C, Vareille-Delarbre M, Gainche M, Berry A, Senejoux F, Ripoche I, Delort L, Vermerie M, Fraisse D, Felgines C, Ranouille E, Berthon JY, Priam J, Saunier E, Tourrette A, Troin Y, Thebaud G, Chalard P, Caldefie-Chezet F. Cholet J, et al. Among authors: troin y. Medicines (Basel). 2019 Oct 11;6(4):101. doi: 10.3390/medicines6040101. Medicines (Basel). 2019. PMID: 31614667 Free PMC article.
Synthesis and Biological Evaluation of New Naphthoquinones Derivatives.
Ourhzif EM, Decombat C, Abrunhosa-Thomas I, Delort L, Khouili M, Akssira M, Caldefie-Chezet F, Chalard P, Troin Y. Ourhzif EM, et al. Among authors: troin y. Curr Org Synth. 2020;17(3):224-229. doi: 10.2174/1570179417666200212111956. Curr Org Synth. 2020. PMID: 32091341
Anti-Inflammatory and Cytotoxic Potential of New Phenanthrenoids from Luzula Sylvatica.
Gainche M, Ripoche I, Senejoux F, Cholet J, Ogeron C, Decombat C, Danton O, Delort L, Vareille-Delarbre M, Berry A, Vermerie M, Fraisse D, Felgines C, Ranouille E, Berthon JY, Priam J, Saunier E, Tourette A, Troin Y, Caldefie-Chezet F, Chalard P. Gainche M, et al. Among authors: troin y. Molecules. 2020 May 20;25(10):2372. doi: 10.3390/molecules25102372. Molecules. 2020. PMID: 32443866 Free PMC article.
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