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NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Furthmann N, Bader V, Angersbach L, Blusch A, Goel S, Sánchez-Vicente A, Krause LJ, Chaban SA, Grover P, Trinkaus VA, van Well EM, Jaugstetter M, Tschulik K, Damgaard RB, Saft C, Ellrichmann G, Gold R, Koch A, Englert B, Westenberger A, Klein C, Jungbluth L, Sachse C, Behrends C, Glatzel M, Hartl FU, Nakamura K, Christine CW, Huang EJ, Tatzelt J, Winklhofer KF. Furthmann N, et al. Among authors: trinkaus va. Nat Commun. 2023 Dec 19;14(1):8368. doi: 10.1038/s41467-023-44033-0. Nat Commun. 2023. PMID: 38114471 Free PMC article.
In situ architecture of neuronal α-Synuclein inclusions.
Trinkaus VA, Riera-Tur I, Martínez-Sánchez A, Bäuerlein FJB, Guo Q, Arzberger T, Baumeister W, Dudanova I, Hipp MS, Hartl FU, Fernández-Busnadiego R. Trinkaus VA, et al. Nat Commun. 2021 Apr 14;12(1):2110. doi: 10.1038/s41467-021-22108-0. Nat Commun. 2021. PMID: 33854052 Free PMC article.