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Multi-omic network analysis identified betacellulin as a novel target of omega-3 fatty acid attenuation of western diet-induced nonalcoholic steatohepatitis.
Padiadpu J, Garcia-Jaramillo M, Newman NK, Pederson JW, Rodrigues R, Li Z, Singh S, Monnier P, Trinchieri G, Brown K, Dzutsev AK, Shulzhenko N, Jump DB, Morgun A. Padiadpu J, et al. Among authors: trinchieri g. EMBO Mol Med. 2023 Nov 8;15(11):e18367. doi: 10.15252/emmm.202318367. Epub 2023 Oct 20. EMBO Mol Med. 2023. PMID: 37859621 Free PMC article.
Early transcriptome changes associated with western diet induced NASH in Ldlr-/- mice points to activation of hepatic macrophages and an acute phase response.
Padiadpu J, Spooner MH, Li Z, Newman N, Löhr CV, Apperson KD, Dzutsev A, Trinchieri G, Shulzhenko N, Morgun A, Jump DB. Padiadpu J, et al. Among authors: trinchieri g. Front Nutr. 2023 Aug 7;10:1147602. doi: 10.3389/fnut.2023.1147602. eCollection 2023. Front Nutr. 2023. PMID: 37609485 Free PMC article.
Cachexia causes time-dependent activation of the inflammasome in the liver.
das Neves RX, Yamashita AS, Riccardi DMR, Köhn-Gaone J, Camargo RG, Neto NI, Caetano D, Gomes SP, Santos FH, Lima JDCC, Batista ML Jr, Rosa-Neto JC, Martins De Alcântara PS, Maximiano LF, Otoch JP, Trinchieri G, Tirnitz-Parker JEE, Seelaender M. das Neves RX, et al. Among authors: trinchieri g. J Cachexia Sarcopenia Muscle. 2023 Aug;14(4):1621-1630. doi: 10.1002/jcsm.13236. Epub 2023 May 12. J Cachexia Sarcopenia Muscle. 2023. PMID: 37177862 Free PMC article.
The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh WT, Gong W, Yoshimura T, Huang J, O'hUigin C, Difilippantonio S, McCollum M, Jones G, Durum SK, Trinchieri G, Wang JM. Chen K, et al. Among authors: trinchieri g. Gut Pathog. 2023 Jun 15;15(1):28. doi: 10.1186/s13099-023-00557-w. Gut Pathog. 2023. PMID: 37322488 Free PMC article.
Correction: The beneficial effects of commensal E. coli for colon epithelial cell recovery are related with Formyl peptide receptor 2 (Fpr2) in epithelial cells.
Chen K, McCulloch J, Das Neves R, Rodrigues G, Hsieh WT, Gong W, Yoshimura T, Huang J, O'hUigin C, Diflippantonio S, McCollum M, Jones G, Durum SK, Trinchieri G, Wang JM. Chen K, et al. Among authors: trinchieri g. Gut Pathog. 2023 Nov 30;15(1):60. doi: 10.1186/s13099-023-00585-6. Gut Pathog. 2023. PMID: 38037170 Free PMC article. No abstract available.
Epithelial-derived interleukin-23 promotes oral mucosal immunopathology.
Kim TS, Ikeuchi T, Theofilou VI, Williams DW, Greenwell-Wild T, June A, Adade EE, Li L, Abusleme L, Dutzan N, Yuan Y, Brenchley L, Bouladoux N, Sakamachi Y; NIDCD/NIDCR Genomics and Computational Biology Core; Palmer RJ Jr, Iglesias-Bartolome R, Trinchieri G, Garantziotis S, Belkaid Y, Valm AM, Diaz PI, Holland SM, Moutsopoulos NM. Kim TS, et al. Among authors: trinchieri g. Immunity. 2024 Apr 9;57(4):859-875.e11. doi: 10.1016/j.immuni.2024.02.020. Epub 2024 Mar 20. Immunity. 2024. PMID: 38513665
Transkingdom Network Analysis (TkNA): a systems framework for inferring causal factors underlying host-microbiota and other multi-omic interactions.
Newman NK, Macovsky MS, Rodrigues RR, Bruce AM, Pederson JW, Padiadpu J, Shan J, Williams J, Patil SS, Dzutsev AK, Shulzhenko N, Trinchieri G, Brown K, Morgun A. Newman NK, et al. Among authors: trinchieri g. Nat Protoc. 2024 Mar 12. doi: 10.1038/s41596-024-00960-w. Online ahead of print. Nat Protoc. 2024. PMID: 38472495 Review.
Deep phenotyping of post-infectious myalgic encephalomyelitis/chronic fatigue syndrome.
Walitt B, Singh K, LaMunion SR, Hallett M, Jacobson S, Chen K, Enose-Akahata Y, Apps R, Barb JJ, Bedard P, Brychta RJ, Buckley AW, Burbelo PD, Calco B, Cathay B, Chen L, Chigurupati S, Chen J, Cheung F, Chin LMK, Coleman BW, Courville AB, Deming MS, Drinkard B, Feng LR, Ferrucci L, Gabel SA, Gavin A, Goldstein DS, Hassanzadeh S, Horan SC, Horovitz SG, Johnson KR, Govan AJ, Knutson KM, Kreskow JD, Levin M, Lyons JJ, Madian N, Malik N, Mammen AL, McCulloch JA, McGurrin PM, Milner JD, Moaddel R, Mueller GA, Mukherjee A, Muñoz-Braceras S, Norato G, Pak K, Pinal-Fernandez I, Popa T, Reoma LB, Sack MN, Safavi F, Saligan LN, Sellers BA, Sinclair S, Smith B, Snow J, Solin S, Stussman BJ, Trinchieri G, Turner SA, Vetter CS, Vial F, Vizioli C, Williams A, Yang SB; Center for Human Immunology, Autoimmunity, and Inflammation (CHI) Consortium; Nath A. Walitt B, et al. Among authors: trinchieri g. Nat Commun. 2024 Feb 21;15(1):907. doi: 10.1038/s41467-024-45107-3. Nat Commun. 2024. PMID: 38383456 Free PMC article.
480 results