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Potential therapies for acute-on-chronic liver failure.
Morrison MA, Artru F, Trovato FM, Triantafyllou E, McPhail MJ. Morrison MA, et al. Among authors: triantafyllou e. Liver Int. 2023 Feb 17. doi: 10.1111/liv.15545. Online ahead of print. Liver Int. 2023. PMID: 36800487 Review.
Patients with acute-on-chronic liver failure have increased numbers of regulatory immune cells expressing the receptor tyrosine kinase MERTK.
Bernsmeier C, Pop OT, Singanayagam A, Triantafyllou E, Patel VC, Weston CJ, Curbishley S, Sadiq F, Vergis N, Khamri W, Bernal W, Auzinger G, Heneghan M, Ma Y, Jassem W, Heaton ND, Adams DH, Quaglia A, Thursz MR, Wendon J, Antoniades CG. Bernsmeier C, et al. Among authors: triantafyllou e. Gastroenterology. 2015 Mar;148(3):603-615.e14. doi: 10.1053/j.gastro.2014.11.045. Epub 2014 Dec 3. Gastroenterology. 2015. PMID: 25479139 Free article.
Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis.
McPhail MJW, Shawcross DL, Lewis MR, Coltart I, Want EJ, Antoniades CG, Veselkov K, Triantafyllou E, Patel V, Pop O, Gomez-Romero M, Kyriakides M, Zia R, Abeles RD, Crossey MME, Jassem W, O'Grady J, Heaton N, Auzinger G, Bernal W, Quaglia A, Coen M, Nicholson JK, Wendon JA, Holmes E, Taylor-Robinson SD. McPhail MJW, et al. Among authors: triantafyllou e. J Hepatol. 2016 May;64(5):1058-1067. doi: 10.1016/j.jhep.2016.01.003. Epub 2016 Jan 18. J Hepatol. 2016. PMID: 26795831 Free PMC article.
PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury.
Triantafyllou E, Gudd CL, Mawhin MA, Husbyn HC, Trovato FM, Siggins MK, O'Connor T, Kudo H, Mukherjee SK, Wendon JA, Bernsmeier C, Goldin RD, Botto M, Khamri W, McPhail MJ, Possamai LA, Woollard KJ, Antoniades CG, Thursz MR. Triantafyllou E, et al. J Clin Invest. 2021 Feb 15;131(4):e140196. doi: 10.1172/JCI140196. J Clin Invest. 2021. PMID: 33320839 Free PMC article.
Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid-Dependent Monocyte Activation.
Trovato FM, Zia R, Napoli S, Wolfer K, Huang X, Morgan PE, Husbyn H, Elgosbi M, Lucangeli M, Miquel R, Wilson I, Heaton ND, Heneghan MA, Auzinger G, Antoniades CG, Wendon JA, Patel VC, Coen M, Triantafyllou E, McPhail MJ. Trovato FM, et al. Among authors: triantafyllou e. Hepatology. 2021 Aug;74(2):907-925. doi: 10.1002/hep.31738. Epub 2021 Jun 15. Hepatology. 2021. PMID: 33908067
Suppressor CD4+ T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis.
Khamri W, Gudd C, Liu T, Nathwani R, Krasniqi M, Azam S, Barbera T, Trovato FM, Possamai L, Triantafyllou E, Seoane RC, Lebosse F, Singanayagam A, Kumar N, Bernsmeier C, Mukherjee S, McPhail M, Weston CJ, Antoniades CG, Thursz MR. Khamri W, et al. Among authors: triantafyllou e. Gut. 2022 Jun;71(6):1192-1202. doi: 10.1136/gutjnl-2021-324071. Epub 2021 Aug 3. Gut. 2022. PMID: 34344786 Free PMC article.
Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure.
Trovato FM, Zia R, Artru F, Mujib S, Jerome E, Cavazza A, Coen M, Wilson I, Holmes E, Morgan P, Singanayagam A, Bernsmeier C, Napoli S, Bernal W, Wendon J, Miquel R, Menon K, Patel VC, Smith J, Atkinson SR, Triantafyllou E, McPhail MJW. Trovato FM, et al. Among authors: triantafyllou e. J Hepatol. 2023 Mar;78(3):558-573. doi: 10.1016/j.jhep.2022.10.031. Epub 2022 Nov 9. J Hepatol. 2023. PMID: 36370949 Free article.
85 results