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Protein disulfide isomerase-mediated transcriptional upregulation of Nox1 contributes to vascular dysfunction in hypertension.
Camargo LL, Trevelin SC, da Silva GHG, Dos Santos Dias AA, Oliveira MA, Mikhaylichenko O, Androwiki ACD, Dos Santos CX, Holbrook LM, Ceravolo GS, Denadai-Souza A, Ribeiro IMR, Sartoretto S, Laurindo FRM, Coltri PP, Antunes VR, Touyz R, Miller FJ Jr, Shah AM, Lopes LR. Camargo LL, et al. Among authors: trevelin sc. J Hypertens. 2024 Jun 1;42(6):984-999. doi: 10.1097/HJH.0000000000003677. Epub 2024 Mar 1. J Hypertens. 2024. PMID: 38690903
Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity.
Romeo SG, Secco I, Schneider E, Reumiller CM, Santos CXC, Zoccarato A, Musale V, Pooni A, Yin X, Theofilatos K, Trevelin SC, Zeng L, Mann GE, Pathak V, Harkin K, Stitt AW, Medina RJ, Margariti A, Mayr M, Shah AM, Giacca M, Zampetaki A. Romeo SG, et al. Among authors: trevelin sc. Nat Commun. 2023 Sep 9;14(1):5552. doi: 10.1038/s41467-023-41326-2. Nat Commun. 2023. PMID: 37689702 Free PMC article.
Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.
Vaikunthanathan T, Landmann E, Correa DM, Romano M, Trevelin SC, Peng Q, Crespo E, Corrado M, Lozano JJ, Pearce EL, Perpinan E, Zoccarato A, Siew L, Edwards-Hicks J, Khan R, Luu NT, Thursz MR, Newsome PN, Martinez-Llordella M, Shah N, Lechler RI, Shah AM, Sanchez-Fueyo A, Lombardi G, Safinia N. Vaikunthanathan T, et al. Among authors: trevelin sc. EBioMedicine. 2023 Sep;95:104778. doi: 10.1016/j.ebiom.2023.104778. Epub 2023 Aug 30. EBioMedicine. 2023. PMID: 37657135 Free PMC article.
Nrf2 attenuates the innate immune response after experimental myocardial infarction.
Bromage DI, Trevelin SC, Huntington J, Yang VX, Muthukumar A, Mackie SJ, Sawyer G, Zhang X, Santos CXC, Safinia N, Smyrnias I, Giacca M, Ivetic A, Shah AM. Bromage DI, et al. Among authors: trevelin sc. Biochem Biophys Res Commun. 2022 May 28;606:10-16. doi: 10.1016/j.bbrc.2022.03.043. Epub 2022 Mar 19. Biochem Biophys Res Commun. 2022. PMID: 35338853 Free article.
Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Estcourt LJ, Turgeon AF, McQuilten ZK, McVerry BJ, Al-Beidh F, Annane D, Arabi YM, Arnold DM, Beane A, Bégin P, van Bentum-Puijk W, Berry LR, Bhimani Z, Birchall JE, Bonten MJM, Bradbury CA, Brunkhorst FM, Buxton M, Callum JL, Chassé M, Cheng AC, Cove ME, Daly J, Derde L, Detry MA, De Jong M, Evans A, Fergusson DA, Fish M, Fitzgerald M, Foley C, Goossens H, Gordon AC, Gosbell IB, Green C, Haniffa R, Harvala H, Higgins AM, Hills TE, Hoad VC, Horvat C, Huang DT, Hudson CL, Ichihara N, Laing E, Lamikanra AA, Lamontagne F, Lawler PR, Linstrum K, Litton E, Lorenzi E, MacLennan S, Marshall J, McAuley DF, McDyer JF, McGlothlin A, McGuinness S, Miflin G, Montgomery S, Mouncey PR, Murthy S, Nichol A, Parke R, Parker JC, Priddee N, Purcell DFJ, Reyes LF, Richardson P, Robitaille N, Rowan KM, Rynne J, Saito H, Santos M, Saunders CT, Serpa Neto A, Seymour CW, Silversides JA, Tinmouth AA, Triulzi DJ, Turner AM, van de Veerdonk F, Walsh TS, Wood EM, Berry S, Lewis RJ, Menon DK, McArthur C, Zarychanski R, Angus DC, Webb SA, Roberts DJ, Shankar-Hari M. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2021 Nov 2;326(17):1690-1702. doi: 10.1001/jama.2021.18178. JAMA. 2021. PMID: 34606578 Free PMC article. Clinical Trial.
Fibroblast Nox2 (NADPH Oxidase-2) Regulates ANG II (Angiotensin II)-Induced Vascular Remodeling and Hypertension via Paracrine Signaling to Vascular Smooth Muscle Cells.
Harrison CB, Trevelin SC, Richards DA, Santos CXC, Sawyer G, Markovinovic A, Zhang X, Zhang M, Brewer AC, Yin X, Mayr M, Shah AM. Harrison CB, et al. Among authors: trevelin sc. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):698-710. doi: 10.1161/ATVBAHA.120.315322. Epub 2020 Oct 15. Arterioscler Thromb Vasc Biol. 2021. PMID: 33054395 Free PMC article.
25 results