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Development of Ternary Amorphous Solid Dispersions Manufactured by Hot-Melt Extrusion and Spray-Drying─Comparison of In Vitro and In Vivo Performance.
Mol Pharm. 2024 Mar 4;21(3):1309-1320. doi: 10.1021/acs.molpharmaceut.3c00696. Epub 2024 Feb 12.
Mol Pharm. 2024.
PMID: 38345459
Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics.
Gerckens M, Schorpp K, Pelizza F, Wögrath M, Reichau K, Ma H, Dworsky AM, Sengupta A, Stoleriu MG, Heinzelmann K, Merl-Pham J, Irmler M, Alsafadi HN, Trenkenschuh E, Sarnova L, Jirouskova M, Frieß W, Hauck SM, Beckers J, Kneidinger N, Behr J, Hilgendorff A, Hadian K, Lindner M, Königshoff M, Eickelberg O, Gregor M, Plettenburg O, Yildirim AÖ, Burgstaller G.
Gerckens M, et al. Among authors: trenkenschuh e.
Sci Adv. 2021 Dec 24;7(52):eabb3673. doi: 10.1126/sciadv.abb3673. Epub 2021 Dec 22.
Sci Adv. 2021.
PMID: 34936468
Free PMC article.
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Freeze-thaw stability of aluminum oxide nanoparticles.
Trenkenschuh E, Friess W.
Trenkenschuh E, et al.
Int J Pharm. 2021 Sep 5;606:120932. doi: 10.1016/j.ijpharm.2021.120932. Epub 2021 Jul 24.
Int J Pharm. 2021.
PMID: 34310956
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Enhancing the Stabilization Potential of Lyophilization for Extracellular Vesicles.
Trenkenschuh E, Richter M, Heinrich E, Koch M, Fuhrmann G, Friess W.
Trenkenschuh E, et al.
Adv Healthc Mater. 2022 Mar;11(5):e2100538. doi: 10.1002/adhm.202100538. Epub 2021 Jul 26.
Adv Healthc Mater. 2022.
PMID: 34310074
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Formulation, process, and storage strategies for lyophilizates of lipophilic nanoparticulate systems established based on the two models paliperidone palmitate and solid lipid nanoparticles.
Trenkenschuh E, Savšek U, Friess W.
Trenkenschuh E, et al.
Int J Pharm. 2021 Sep 5;606:120929. doi: 10.1016/j.ijpharm.2021.120929. Epub 2021 Jul 23.
Int J Pharm. 2021.
PMID: 34303819
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Freeze-drying of nanoparticles: How to overcome colloidal instability by formulation and process optimization.
Trenkenschuh E, Friess W.
Trenkenschuh E, et al.
Eur J Pharm Biopharm. 2021 Aug;165:345-360. doi: 10.1016/j.ejpb.2021.05.024. Epub 2021 May 27.
Eur J Pharm Biopharm. 2021.
PMID: 34052428
Review.
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