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N-3 PUFA deficiency disrupts oligodendrocyte maturation and myelin integrity during brain development.
Leyrolle Q, Decoeur F, Dejean C, Brière G, Leon S, Bakoyiannis I, Baroux E, Sterley TL, Bosch-Bouju C, Morel L, Amadieu C, Lecours C, St-Pierre MK, Bordeleau M, De Smedt-Peyrusse V, Séré A, Schwendimann L, Grégoire S, Bretillon L, Acar N, Joffre C, Ferreira G, Uricaru R, Thebault P, Gressens P, Tremblay ME, Layé S, Nadjar A. Leyrolle Q, et al. Among authors: tremblay me. Glia. 2022 Jan;70(1):50-70. doi: 10.1002/glia.24088. Epub 2021 Sep 14. Glia. 2022. PMID: 34519378
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Smith PY, Hernandez-Rapp J, Jolivette F, Lecours C, Bisht K, Goupil C, Dorval V, Parsi S, Morin F, Planel E, Bennett DA, Fernandez-Gomez FJ, Sergeant N, Buée L, Tremblay MÈ, Calon F, Hébert SS. Smith PY, et al. Among authors: tremblay me. Hum Mol Genet. 2015 Dec 1;24(23):6721-35. doi: 10.1093/hmg/ddv377. Epub 2015 Sep 11. Hum Mol Genet. 2015. PMID: 26362250 Free PMC article.
Dark microglia: A new phenotype predominantly associated with pathological states.
Bisht K, Sharma KP, Lecours C, Sánchez MG, El Hajj H, Milior G, Olmos-Alonso A, Gómez-Nicola D, Luheshi G, Vallières L, Branchi I, Maggi L, Limatola C, Butovsky O, Tremblay MÈ. Bisht K, et al. Among authors: tremblay me. Glia. 2016 May;64(5):826-39. doi: 10.1002/glia.22966. Epub 2016 Feb 5. Glia. 2016. PMID: 26847266 Free PMC article.
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling.
Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Domercq M, Pérez-Samartín A, Sánchez-Zafra V, Paris I, Valero J, Savage JC, Hui CW, Tremblay MÈ, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco Md, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. Abiega O, et al. Among authors: tremblay me. PLoS Biol. 2016 May 26;14(5):e1002466. doi: 10.1371/journal.pbio.1002466. eCollection 2016 May. PLoS Biol. 2016. PMID: 27228556 Free PMC article.
Microglia Gone Rogue: Impacts on Psychiatric Disorders across the Lifespan.
Tay TL, Béchade C, D'Andrea I, St-Pierre MK, Henry MS, Roumier A, Tremblay ME. Tay TL, et al. Among authors: tremblay me. Front Mol Neurosci. 2018 Jan 4;10:421. doi: 10.3389/fnmol.2017.00421. eCollection 2017. Front Mol Neurosci. 2018. PMID: 29354029 Free PMC article. Review.
Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
Hui CW, St-Pierre MK, Detuncq J, Aumailley L, Dubois MJ, Couture V, Skuk D, Marette A, Tremblay JP, Lebel M, Tremblay MÈ. Hui CW, et al. Among authors: tremblay me, tremblay jp. Brain Behav Immun. 2018 Oct;73:450-469. doi: 10.1016/j.bbi.2018.06.007. Epub 2018 Jun 15. Brain Behav Immun. 2018. PMID: 29908963
207 results