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miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Smith PY, Hernandez-Rapp J, Jolivette F, Lecours C, Bisht K, Goupil C, Dorval V, Parsi S, Morin F, Planel E, Bennett DA, Fernandez-Gomez FJ, Sergeant N, Buée L, Tremblay MÈ, Calon F, Hébert SS. Smith PY, et al. Among authors: tremblay me. Hum Mol Genet. 2015 Dec 1;24(23):6721-35. doi: 10.1093/hmg/ddv377. Epub 2015 Sep 11. Hum Mol Genet. 2015. PMID: 26362250 Free PMC article.
Dark microglia: A new phenotype predominantly associated with pathological states.
Bisht K, Sharma KP, Lecours C, Sánchez MG, El Hajj H, Milior G, Olmos-Alonso A, Gómez-Nicola D, Luheshi G, Vallières L, Branchi I, Maggi L, Limatola C, Butovsky O, Tremblay MÈ. Bisht K, et al. Among authors: tremblay me. Glia. 2016 May;64(5):826-39. doi: 10.1002/glia.22966. Epub 2016 Feb 5. Glia. 2016. PMID: 26847266 Free PMC article.
Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling.
Abiega O, Beccari S, Diaz-Aparicio I, Nadjar A, Layé S, Leyrolle Q, Gómez-Nicola D, Domercq M, Pérez-Samartín A, Sánchez-Zafra V, Paris I, Valero J, Savage JC, Hui CW, Tremblay MÈ, Deudero JJ, Brewster AL, Anderson AE, Zaldumbide L, Galbarriatu L, Marinas A, Vivanco Md, Matute C, Maletic-Savatic M, Encinas JM, Sierra A. Abiega O, et al. Among authors: tremblay me. PLoS Biol. 2016 May 26;14(5):e1002466. doi: 10.1371/journal.pbio.1002466. eCollection 2016 May. PLoS Biol. 2016. PMID: 27228556 Free PMC article.
206 results