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Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.
McCormack MP, Shields BJ, Jackson JT, Nasa C, Shi W, Slater NJ, Tremblay CS, Rabbitts TH, Curtis DJ. McCormack MP, et al. Among authors: tremblay cs. Blood. 2013 Sep 19;122(12):2093-103. doi: 10.1182/blood-2012-09-458570. Epub 2013 Aug 7. Blood. 2013. PMID: 23926305 Free article.
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.
Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, Pieters T, Matthijssens F, Van Roy N, Best JA, Deswarte K, Bogaert P, Carmichael C, Rickard A, Suryani S, Bracken LS, Alserihi R, Canté-Barrett K, Haenebalcke L, Clappier E, Rondou P, Slowicka K, Huylebroeck D, Goldrath AW, Janzen V, McCormack MP, Lock RB, Curtis DJ, Harrison C, Berx G, Speleman F, Meijerink JP, Soulier J, Van Vlierberghe P, Haigh JJ. Goossens S, et al. Among authors: tremblay cs. Nat Commun. 2015 Jan 7;6:5794. doi: 10.1038/ncomms6794. Nat Commun. 2015. PMID: 25565005 Free PMC article.
Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.
Tremblay CS, Brown FC, Collett M, Saw J, Chiu SK, Sonderegger SE, Lucas SE, Alserihi R, Chau N, Toribio ML, McCormack MP, Chircop M, Robinson PJ, Jane SM, Curtis DJ. Tremblay CS, et al. Leukemia. 2016 Oct;30(10):1993-2001. doi: 10.1038/leu.2016.100. Epub 2016 Apr 27. Leukemia. 2016. PMID: 27118408
Loss of Dynamin 2 GTPase function results in microcytic anaemia.
Brown FC, Collett M, Tremblay CS, Rank G, De Camilli P, Booth CJ, Bitoun M, Robinson PJ, Kile BT, Jane SM, Curtis DJ. Brown FC, et al. Among authors: tremblay cs. Br J Haematol. 2017 Aug;178(4):616-628. doi: 10.1111/bjh.14709. Epub 2017 May 3. Br J Haematol. 2017. PMID: 28466468 Free article.
A novel role for Lyl1 in primitive erythropoiesis.
Chiu SK, Saw J, Huang Y, Sonderegger SE, Wong NC, Powell DR, Beck D, Pimanda JE, Tremblay CS, Curtis DJ. Chiu SK, et al. Among authors: tremblay cs. Development. 2018 Oct 11;145(19):dev162990. doi: 10.1242/dev.162990. Development. 2018. PMID: 30185409
31 results