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Overexpression of human alpha-Synuclein leads to dysregulated microbiome/metabolites with ageing in a rat model of Parkinson disease.
Singh Y, Trautwein C, Romani J, Salker MS, Neckel PH, Fraccaroli I, Abeditashi M, Woerner N, Admard J, Dhariwal A, Dueholm MKD, Schäfer KH, Lang F, Otzen DE, Lashuel HA, Riess O, Casadei N. Singh Y, et al. Among authors: trautwein c. Mol Neurodegener. 2023 Jul 4;18(1):44. doi: 10.1186/s13024-023-00628-1. Mol Neurodegener. 2023. PMID: 37403161 Free PMC article.
DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs).
Singh Y, Trautwein C, Dhariwal A, Salker MS, Alauddin M, Zizmare L, Pelzl L, Feger M, Admard J, Casadei N, Föller M, Pachauri V, Park DS, Mak TW, Frick JS, Wallwiener D, Brucker SY, Lang F, Riess O. Singh Y, et al. Among authors: trautwein c. Sci Rep. 2020 Sep 30;10(1):16131. doi: 10.1038/s41598-020-72903-w. Sci Rep. 2020. PMID: 32999308 Free PMC article.
Human Dopaminergic Neurons Lacking PINK1 Exhibit Disrupted Dopamine Metabolism Related to Vitamin B6 Co-Factors.
Bus C, Zizmare L, Feldkaemper M, Geisler S, Zarani M, Schaedler A, Klose F, Admard J, Mageean CJ, Arena G, Fallier-Becker P, Ugun-Klusek A, Maruszczak KK, Kapolou K, Schmid B, Rapaport D, Ueffing M, Casadei N, Krüger R, Gasser T, Vogt Weisenhorn DM, Kahle PJ, Trautwein C, Gloeckner CJ, Fitzgerald JC. Bus C, et al. Among authors: trautwein c. iScience. 2020 Nov 13;23(12):101797. doi: 10.1016/j.isci.2020.101797. eCollection 2020 Dec 18. iScience. 2020. PMID: 33299968 Free PMC article.
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cells.
Singh Y, Trautwein C, Fendel R, Krickeberg N, Berezhnoy G, Bissinger R, Ossowski S, Salker MS, Casadei N, Riess O; Deutsche COVID-19 OMICS Initiate (DeCOI). Singh Y, et al. Among authors: trautwein c. Heliyon. 2021 Jun;7(6):e07147. doi: 10.1016/j.heliyon.2021.e07147. Epub 2021 May 28. Heliyon. 2021. PMID: 34075347 Free PMC article.
Quantitative Serum NMR Spectroscopy Stratifies COVID-19 Patients and Sheds Light on Interfaces of Host Metabolism and the Immune Response with Cytokines and Clinical Parameters.
Rössler T, Berezhnoy G, Singh Y, Cannet C, Reinsperger T, Schäfer H, Spraul M, Kneilling M, Merle U, Trautwein C. Rössler T, et al. Among authors: trautwein c. Metabolites. 2022 Dec 16;12(12):1277. doi: 10.3390/metabo12121277. Metabolites. 2022. PMID: 36557315 Free PMC article.
Urinary phenotyping of SARS-CoV-2 infection connects clinical diagnostics with metabolomics and uncovers impaired NAD+ pathway and SIRT1 activation.
Lonati C, Berezhnoy G, Lawler N, Masuda R, Kulkarni A, Sala S, Nitschke P, Zizmare L, Bucci D, Cannet C, Schäfer H, Singh Y, Gray N, Lodge S, Nicholson J, Merle U, Wist J, Trautwein C. Lonati C, et al. Among authors: trautwein c. Clin Chem Lab Med. 2023 Nov 14;62(4):770-788. doi: 10.1515/cclm-2023-1017. Print 2024 Mar 25. Clin Chem Lab Med. 2023. PMID: 37955280 Free article.
Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients.
Sala S, Nitschke P, Masuda R, Gray N, Lawler NG, Wood JM, Buckler JN, Berezhnoy G, Bolaños J, Boughton BA, Lonati C, Rössler T, Singh Y, Wilson ID, Lodge S, Morillon AC, Loo RL, Hall D, Whiley L, Evans GB, Grove TL, Almo SC, Harris LD, Holmes E, Merle U, Trautwein C, Nicholson JK, Wist J. Sala S, et al. Among authors: trautwein c. J Proteome Res. 2024 Mar 1;23(3):956-970. doi: 10.1021/acs.jproteome.3c00654. Epub 2024 Feb 4. J Proteome Res. 2024. PMID: 38310443 Free PMC article.
842 results