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Page 1
Sarcoma treatment in the era of molecular medicine.
Grünewald TG, Alonso M, Avnet S, Banito A, Burdach S, Cidre-Aranaz F, Di Pompo G, Distel M, Dorado-Garcia H, Garcia-Castro J, González-González L, Grigoriadis AE, Kasan M, Koelsche C, Krumbholz M, Lecanda F, Lemma S, Longo DL, Madrigal-Esquivel C, Morales-Molina Á, Musa J, Ohmura S, Ory B, Pereira-Silva M, Perut F, Rodriguez R, Seeling C, Al Shaaili N, Shaabani S, Shiavone K, Sinha S, Tomazou EM, Trautmann M, Vela M, Versleijen-Jonkers YM, Visgauss J, Zalacain M, Schober SJ, Lissat A, English WR, Baldini N, Heymann D. Grünewald TG, et al. Among authors: trautmann m. EMBO Mol Med. 2020 Nov 6;12(11):e11131. doi: 10.15252/emmm.201911131. Epub 2020 Oct 13. EMBO Mol Med. 2020. PMID: 33047515 Free PMC article. Review.
Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information.
Koelsche C, Hartmann W, Schrimpf D, Stichel D, Jabar S, Ranft A, Reuss DE, Sahm F, Jones DTW, Bewerunge-Hudler M, Trautmann M, Klingebiel T, Vokuhl C, Gessler M, Wardelmann E, Petersen I, Baumhoer D, Flucke U, Antonescu C, Esteller M, Fröhling S, Kool M, Pfister SM, Mechtersheimer G, Dirksen U, von Deimling A. Koelsche C, et al. Among authors: trautmann m. Mod Pathol. 2018 Aug;31(8):1246-1256. doi: 10.1038/s41379-018-0045-3. Epub 2018 Mar 23. Mod Pathol. 2018. PMID: 29572501 Free PMC article.
Focal adhesion kinase confers pro-migratory and antiapoptotic properties and is a potential therapeutic target in Ewing sarcoma.
Steinestel K, Trautmann M, Jansen EP, Dirksen U, Rehkämper J, Mikesch JH, Gerke JS, Orth MF, Sannino G, Arteaga MF, Rossig C, Wardelmann E, Grünewald TGP, Hartmann W. Steinestel K, et al. Among authors: trautmann m. Mol Oncol. 2020 Feb;14(2):248-260. doi: 10.1002/1878-0261.12610. Epub 2019 Dec 21. Mol Oncol. 2020. PMID: 31811703 Free PMC article.
Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma.
Berthold R, Isfort I, Erkut C, Heinst L, Grünewald I, Wardelmann E, Kindler T, Åman P, Grünewald TGP, Cidre-Aranaz F, Trautmann M, Fröhling S, Scholl C, Hartmann W. Berthold R, et al. Among authors: trautmann m. Oncogenesis. 2022 Apr 22;11(1):20. doi: 10.1038/s41389-022-00394-7. Oncogenesis. 2022. PMID: 35459264 Free PMC article.
Phosphatidylinositol-3'-kinase/AKT signaling is essential in synovial sarcoma.
Friedrichs N, Trautmann M, Endl E, Sievers E, Kindler D, Wurst P, Czerwitzki J, Steiner S, Renner M, Penzel R, Koch A, Larsson O, Tanaka S, Kawai A, Schirmacher P, Mechtersheimer G, Wardelmann E, Buettner R, Hartmann W. Friedrichs N, et al. Among authors: trautmann m. Int J Cancer. 2011 Oct 1;129(7):1564-75. doi: 10.1002/ijc.25829. Epub 2011 Mar 4. Int J Cancer. 2011. PMID: 21128248 Free article.
Requirement for YAP1 signaling in myxoid liposarcoma.
Trautmann M, Cheng YY, Jensen P, Azoitei N, Brunner I, Hüllein J, Slabicki M, Isfort I, Cyra M, Berthold R, Wardelmann E, Huss S, Altvater B, Rossig C, Hafner S, Simmet T, Ståhlberg A, Åman P, Zenz T, Lange U, Kindler T, Scholl C, Hartmann W, Fröhling S. Trautmann M, et al. EMBO Mol Med. 2019 May;11(5):e9889. doi: 10.15252/emmm.201809889. EMBO Mol Med. 2019. PMID: 30898787 Free PMC article.
Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone.
Isfort I, Elges S, Cyra M, Berthold R, Renner M, Mechtersheimer G, Åman P, Larsson O, Ratner N, Hafner S, Simmet T, Schliemann C, Rossig C, Dirksen U, Grünewald I, Wardelmann E, Huss S, Hartmann W, Trautmann M. Isfort I, et al. Among authors: trautmann m. Sci Rep. 2019 Dec 23;9(1):19704. doi: 10.1038/s41598-019-56247-8. Sci Rep. 2019. PMID: 31873172 Free PMC article.
SS18-SSX drives CREB activation in synovial sarcoma.
Cyra M, Schulte M, Berthold R, Heinst L, Jansen EP, Grünewald I, Elges S, Larsson O, Schliemann C, Steinestel K, Hafner S, Simmet T, Wardelmann E, Kailayangiri S, Rossig C, Isfort I, Trautmann M, Hartmann W. Cyra M, et al. Among authors: trautmann m. Cell Oncol (Dordr). 2022 Jun;45(3):399-413. doi: 10.1007/s13402-022-00673-w. Epub 2022 May 12. Cell Oncol (Dordr). 2022. PMID: 35556229 Free PMC article.
318 results